Since 2016 Group Leader of Pathometabolism group, TU Braunschweig Topics: Pathological alterations of mammalian metabolism, computational modeling of human metabolism
2014 – 2016 Postdoc, University of Luxembourg Topics: Analysis of human metabolism using stable-isotopes
2012 – 2013 Visiting scholar, Massachusetts Institute of Technology, Department of Chemical Engineering Topics: 13C-Metabolic Flux Analysis
2011 – 2013 Graduate student, University of Luxembourg Topics: Mass-Spectrometry, Human Metabolism, Stable-Isotope Labelling PhD thesis: Computational tools for mass spectrometry based metabolic profiling
2003 – 2010 Study of Bioinformatics and Computer Science, University of Tuebingen
Nonnenmacher, Y., Palorini R., Fouquier d'Herouel, A., Krämer, L., Neumann-Schaal, M., Chiaradonna, F., W., Skupin, A., Wegner, A., Hiller, K. Analysis of mitochondrial metabolism in situ: Combining stable isotope labeling with selective permeabilization. Metab Eng. 2017 Sep;43(Pt B):147-155
2016
Weindl D, Wegner A., Hiller K. MIA: non-targeted mass isotopolome analysis. Bioinformatics. 2016 Sep 15;32(18):2875-6.
Weindl D, Cordes T, Battello N, Sapcariu SC, Dong X, Wegner A, Hiller K. Bridging the gap between non-targeted stable isotope labeling and metabolic flux analysis. Cancer Metab. 2016 Apr 23;4:10.
Battello N, Zimmer AD, Goebel C, Dong X, Behrmann I, Haan C, Hiller K, Wegner A The role of HIF-1 in oncostatin M-dependent metabolic reprogramming of hepatic cells. Cancer Metab. 2016 Feb 17;4:3.
2015
Weindl D, Wegner A, Hiller K. Metabolome-Wide Analysis of Stable Isotope Labeling-Is It Worth the Effort? Front Physiol. 2015 Nov 20;6:344.
Venturelli S, Belz RG, Kämper A, Berger A, von Horn K, Wegner A, Böcker A, Zabulon G, Langenecker T, Kohlbacher O, Barneche F, Weigel D, Lauer UM, Bitzer M, Becker C. Plants Release Precursors of Histone Deacetylase Inhibitors to Suppress Growth of Competitors. Plant Cell. 2015 Nov;27(11):3175-89.
Weindl D, Wegner A, Hiller K. Non-targeted Tracer Fate Detection. Methods Enzymol. 2015;561:277-302.
Weindl D, Wegner A, Jäger C, Hiller K. Isotopologue ratio normalization for non-targeted metabolomics. J Chromatogr A. 2015 Apr 10;1389:112-9.
Wegner A, Meiser J, Weindl D, Hiller K. How metabolites modulate metabolic flux. Curr Opin Biotechnol. 2015 Aug;34:16-22.
2014
Wegner A, Weindl D, Jäger C, Sapcariu SC, Dong X, Stephanopoulos G, Hiller K. Fragment formula calculator (FFC): determination of chemical formulas for fragment ions in mass spectrometric data. Anal Chem. 2014 Feb 18;86(4):2221-8.
2013
McGuirk S, Gravel SP, Deblois G, Papadopoli DJ, Faubert B, Wegner A, Hiller K, Avizonis D, Akavia UD, Jones RG, Giguère V, St-Pierre J. PGC-1α supports glutamine metabolism in breast cancer. Cancer Metab. 2013 Dec 5;1(1):22.
Michelucci A, Cordes T, Ghelfi J, Pailot A, Reiling N, Goldmann O, Binz T, Wegner A, Tallam A, Rausell A, Buttini M, Linster CL, Medina E, Balling R, Hiller K. Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production. Proc Natl Acad Sci U S A. 2013 May 7;110(19):7820-5.
Wegner A, Sapcariu SC, Weindl D, Hiller K. Isotope cluster-based compound matching in gas chromatography/mass spectrometry for non-targeted metabolomics. Anal Chem. 2013 Apr 16;85(8):4030-7.
Hiller K, Wegner A, Weindl D, Cordes T, Metallo CM, Kelleher JK, Stephanopoulos G. NTFD--a stand-alone application for the non-targeted detection of stable isotope-labeled compounds in GC/MS data. Bioinformatics. 2013 May 1;29(9):1226-8.
