Die Projektarbeit Mechatronik ist in die Projektarbeit Produktions- und Systemtechnik integriert. Die Anmeldung für beide Vertiefungsrichtungen erfolgt zu Beginn des jeweiligen Semesters über StudIP unter „Projektarbeit Produktions- und Systemtechnik“.
Dies ist die Liste der zur Zeit am IMT ausgeschriebenen Projekt-, Studien-, Bachelor- und Master-Arbeiten.
For gut cell cultures in infection studies to be representative, there is the wish to mimic the biomechanical in-vivo conditions of the cells. Epithelial gut cells in a living body are permanently stimulated by fluid-flow-induced shear stress and mechanical strain.
Responsible: David Jaworski
Epithelial gut cells in a living body are permanently stimulated by fluid-flow-induced shear stress and mechanical strain. In the EpiStretch project, we develop a device that will contribute to infection studies on cells with in-vivo-like biomechanical conditions.
Responsible: David Jaworski
Epithelial gut cells in a living body are permanently stimulated by fluid-flow-induced shear stress and mechanical strain. In the EpiStretch project, we develop a device that will contribute to infection studies on cells with in-vivo-like biomechanical conditions.
Responsible: David Jaworski
The aim of this project is to fabricate PDMS microfluidic for in vivo whole-brain imaging of zebrafish larvae. Such a device needs to accomplish several goals, including integration with the chip with light-sheet microscope. Technical challenges in fabricating with high precision out of PDMS exhibiting a sufficient optical quality and sidewalls that can accommodate the incoming excitation laser is required.
Responsible: Dominika Schrödter
Es wird eine Darstellung eines virtuellen Gameboys erarbeitet, der die genauen Bauteil-Kommunikationsabläufe veranschaulicht. Hierbei wird eine präzise visuelle Darstellung der internen Komponenten und der Datenübertragungen angestrebt, um die Komplexität der Interaktionen greifbar zu machen. Dabei werden erweiterte technische Grafiken und Modelle verwendet, die in Echtzeit die Kommunikation und Datenflüsse zwischen CPU, Speicher und anderen Komponenten des Gameboys visualisiert.
Verantwortlicher: Steven Walter Zander
This work is part of the Homeo Brain project*. The goal of this study is to develop a microfluidic chip (MFC) to define the outgrowth of the neuronal network on a microelectrode array (MEA). The MFC is made of polydimethylsiloxane (PDMS) and separates two culture chambers with a volume of about 100 µl culture medium by an array of microfluidic channels with a cross-sectional area of about 100 µm2. This allows the compartmentalized analysis of different subcellular neuronal compartments, e.g. soma, axons and synapses. For different cell sources, e.g. zebrafish vs. rodents, different channel geometries are required to allow full outgrowth of neuronal extensions. It would be ideal if the student had previous experience in micro- and nanofabrication. The MFC molds will be fabricated by femtosecond laser, photolithography, and stereolithography using the two-photon polymerization technique. The process will take place either in the clean room of IMT or PVZ.
Responsible: Victor Krajka
This work is part of the Homeo Brain project*. The goal is to develop a microelectrode array (MEA) for extracellular recording of neuronal activity. The MEA is a thin chip mounted on a head stage and connected to a computer to measure action potentials and perform various data analyses. The student must be familiar with AutoCAD to construct the MEA. It would be ideal if the student had previous experience in micro- and nano-fabrication. In our project, we need to fabricate electrodes that are arranged to fit perfectly into our custom microfluidic chambers. Right now we have 60 electrodes arranged in a square. Later, the pattern will be changed without affecting the performance. The microelectrodes are fabricated by photolithography, sputtering and etching. The process will take place in IMT's clean room. Students with clean room experience are preferred.
Responsible: Victor Krajka
Das Ziel dieser Arbeit ist die Entwicklung der hochautomatisierten Arbeitsabläufe von modellen, welche Simulationen und Auswertung Algorithmen kombinieren, um die Simulationen beschleunigen zu können.
Responsible: Songtago Cai
Der am IMT vorgeschlagene und gefertigte Point-of-Care Prototyp wird als kostengünstiger, empfindlicher Point-of-Care Biosensor zur Überwachung und Detektion von Viren dienen. Das Ziel dieser Arbeit ist die Erstellung eines Simulationsmodells zum Vorhersagen des Fließverhaltens in den porösen Medien.
Responsible: Songtago Cai
Oxidative and nitrosative stress are directly linked to a wide range of disorders, from Alzheimer’s to schizophrenia. A sensor to measure these stressors could find applications from point-of-care diagnostic aids (labs-on-chips) to functioning as a new research tool in miniaturized disease models (organs-on-chips). The aim of this project is to take a previously-developed optical assay based on a soluble chemical and develop it into a sensor platform by immobilizing or otherwise integrating this chemical compound into microfluidic devices.
Responsible: Dr. Thomas Winkler
Biomedical research largely relies on culture of cells in standardized arrays of culture wells (e.g. 96-plate). The aim of this project is to design a robotic gantry system that can operate inside a cell culture incubator to measure metabolic function and dispense/exchange liquids from such culture plates. The goal is to use standard, low-cost components and provide an open-source design to make it accessible to academic laboratories worldwide.
Responsible: Dr. Thomas Winkler
Lipid nanoparticles (LNPs) is a carrier for medical agents in the human body. Many modern active pharmaceutical ingredients have poor water solubility and strong lipophilic properties. As a result, the need for alternative dosage forms in order to apply these drugs appropriately is increasing. However, the dosage form can be improved by reducing the size of the drug particles, which results in fundamentally different biophysical properties compared to systems with macroparticles, and increases the specific surface area relevant for mass transfer.
Responsible: Ebrahim TaiediNejad
The aim of this project is therefore developing the design and then fabricating the microchannel using etching methods like ICP dry etching and KOH wet etching, and then fabricating the electrodes on top of the channel. If you are interested in microsystem technology, this project will give you a great opportunity to gain experiences in that area.
Responsible: Mohadeseh Mozafari
The aim of this project is to optimize the parameter related to the ablation of PDMS and glass to fabricate a microchannel and at the end, find the threshold parameter in the fs-laser device which is located in IMT. In this project, one may work with a high-tech device, and gain a lot of information about micromachining and microfluidics.
Responsible: Mohadeseh Mozafari
The IMT is working on an open microbioreactor (MBR) in the project "Open capillary wave micro-reactor for biopharmaceutical screening applications". In this work, optical waveguides for measuring optical density in an MBR will be microfabricated and investigated using photolithograpy.
Responsible: Sven Meinen
In this student project the task is to develop a platform which enables to use 9 reactors in parallel by using an axis system to move the reactor platform to the used sensors, which are by now optical sensor spots, read out by optical fibres and a liquid level control, achieved by triangulation measurements.
Responsible: Sven Meinen
The role of electrogenic gut microorganisms in the human intestinal microbiome is not yet fully understood, and available screening methods today are time-consuming, have limited sample throughputs and low detection rates. Therefore, developing a micro-fabricated high-throughput bioelectrochemical flow cytometer detecting gut bacteria is needed.
The aim of this project is to extract the signal related to particles from the noisy signal with the help of a lock-in-amplifier. So a basic knowledge of electronic would be an advantage. The second step after the detection would be an impendence spectroscopy using the same device. During the time-period of this HiWi position you will work with pre-fabricated microfluidics system and the lock-in-amplifier to find the parameter which the goals can be obtained.
Responsible: Mohadeseh Mozafari
This thesis deals with the fabrication of microfluidic channel with IP-Q photoresist in different shape and sizes. IP-Q photoresist is used for High-speed fabrication of millimetre-sized microfluidic chip using Nanoscribe’s high-precision 3D printing technology. The 3D printing of the channel system is achieved with a 2PP system equipped with a near infrared femtosecond laser source.
Responsible: Ebrahim TaiediNejad
Hi! We are MinkTec, a spin-off of the IMT and we want to be the very first company to find and successfully target the causes of non-specific back pain. Our unique sensor shirt is the first easy-to-use technology in the world to track the exact shape of the spine 24/7 and display a personalized 3D-avatar of the user in their mobile app. Using machine learning algorithms, we want to analyze motion patterns of back pain patients to find the causes of their pain. Our app provides tips and tricks for better posture as well as targeted vibration alerts and includes an individualized training plan that is covered by all German Health Insurances.
Ansprechpartner: Benjamin Holmer (benjamin.holmer@minktec.com or +49 176 6122 8869)
Dear Students / Liebe Studierende,
In this project you can do any kind of work to create flexible/stretchable sensor systems! From sensor design/fabrication, over electronics development/fabrication to exciting software development tasks. You can expect interesting tasks at a competent and pleasant working atmosphere!
Just have a look at my website: www.ib-ekoch.de
Die Arbeit kann sowohl in deutscher als auch in englischer Sprache durchgeführt werden.
Feel free to contact me at any time :)
Ansprechpartner: Eugen Koch