Cornelius, J., Haak, S., Rothkegel, M., Korte, M. and Michaelsen-Preusse, K. (2023) Phosphorylation of the actin-binding protein profilin2a at S137 modulates bidirectional structural plasticity at dendritic spines. Front Cell Dev Biol., 11:1107380. doi: 10.3389/fcell.2023.1107380. eCollection 2023.
Li, Q., Navakkode, S., Rothkegel, M., Soong, T.W., Sajikumar, S. and Korte, M. (2017) Metaplasticity mechanisms restore plasticity and associativity in an animal model of Alzheimer's disease. Proc Natl Acad Sci U S A. 2017 May 23;114(21):5527-5532.
Kaufholdt, D., Baillie, C.-K., Bikker, R., Burkart, V., Dudek, C.-A.,von Pein, L., Rothkegel, M. , Mendel, R.R. and Hänsch, R. (2016). The molybdenum cofactor biosynthesis complex interacts with actin filaments via molybdenum insertase Cnx1 as anchor protein in Arabidopsis thaliana. Plant Sci 244, 8-18. doi:10.1016/j.plantsci.2015.12.011
Schweinhuber, S.K., Meßerschmidt, T., Hänsch, R., Korte, M. and Rothkegel, M. (2015). Profilin Isoforms Modulate Astrocytic Morphology and the Motility of Astrocytic Processes. PLoS ONE 10(1): e0117244. doi:10.1371/journal.pone.0117244
Li, Q., Rothkegel, M., Xiao, Z.C., Abraham, W.C., Korte, M. and Sajikumar, S. (2014) Making Synapses Strong: Metaplasticity Prolongs Associativity of Long-Term Memory by Switching Synaptic Tag Mechanisms. Cerebral Cortex 24, 353-363, doi: 10.1093/cercor/bhs315
Murk, K., Wittenmayer, N., Michaelsen-Preusse, K., Dresbach, T., Schoenenberger, C.-A., Korte, M., Jockusch, B.M., and Rothkegel, M. (2012). Neuronal Profilin Isoforms Are Addressed by Different Signalling Pathways. PLoS ONE 7(3): e34167. doi:10.1371/journal.pone.0034167
Michaelsen, K., Murk, K., Zagrebelsky, M., Dreznjak, A., Jockusch, B.M., Rothkegel, M. and Korte, M. (2010). Fine-tuning of neuronal architecture requires two profilin isoforms. Proc Natl Acad Sci U S A 107:15780-15785.
Wahl, B., Reichmann, D., Niks, D., Krompholz, N., Havemeyer, A., Clement, B., Meßerschmidt, T., Rothkegel, M., Biester, H., Hille, R., Mendel, R.R., and Bittner, F. (2010). Biochemical and spectroscopic characterization of the human mitochondrial amidoxime reducing components hmARC-1 and hm ARC-2 suggests the existence of a new molybdenum-enzyme family in eukaryotes. J. Biol. Chem. 285:37847-59.
Behnen, M.*, Murk, K.*, Kursula, P., Cappallo-Obermann, H., Rothkegel, M., Kierszenbaum, A.L. and Kirchhoff, C. (2009). Testis-expressed profilins 3 and 4 show distinct functional characteristics and localize in the acroplaxome-manchette complex in spermatids. BMC Cell Biol., 10:34 (* both authors contributed equally)
Murk, K., Buchmeier, S., Jockusch, B.M. and Rothkegel, M. (2009). In birds, profilin-2a is ubiquitously expressed and contributes to actin-based motility. J. Cell Sci. 122, 957-964
Jockusch, B.M., Murk, K. and Rothkegel, M. (2007). The profile of profilin. Rev. Physiol. Biochem. Pharmacol. 159, 131-49
Lederer, M., Jockusch, B. M., and Rothkegel, M. (2005). Profilin regulates the activity of p42POP, a novel Myb-related transcription factor. J. Cell Sci. 118, 331-341
Jockusch, B. M., Rothkegel, M., and Schwarz, G. (2004). Linking the synapse to the cytoskeleton: a breath-taking role for microfilaments. Neuroreport 15, 1535-1538.
Wittenmayer, N., Jandrig, B., Rothkegel, M., Schluter, K., Arnold, W., Haensch, W., Scherneck, S., and Jockusch, B. M. (2004). Tumor suppressor activity of profilin requires a functional actin binding site. Mol Biol Cell 15, 1600-1608
Giesemann, T., Schwarz, G., Nawrotzki, R., Berhorster, K., Rothkegel, M., Schluter, K., Schrader, N., Schindelin, H., Mendel, R. R., Kirsch, J., and Jockusch, B. M. (2003). Complex formation between the postsynaptic scaffolding protein gephyrin, profilin, and Mena: a possible link to the microfilament system. J Neurosci 23, 8330-8339
Krebs, A., Rothkegel, M., Klar, M., and Jockusch, B. M. (2001). Characterization of functional domains of mDia1, a link between the small GTPase Rho and the actin cytoskeleton. J Cell Sci 114, 3663-3672
Geese, M., Schluter, K., Rothkegel, M., Jockusch, B. M., Wehland, J., and Sechi, A. S. (2000). Accumulation of profilin II at the surface of Listeria is concomitant with the onset of motility and correlates with bacterial speed. J Cell Sci 113, 1415-1426
Wittenmayer, N., Rothkegel, M., Jockusch, B. M., and Schluter, K. (2000). Functional characterization of green fluorescent protein-profilin fusion proteins. Eur J Biochem 267, 5247-5256
Giesemann, T., Rathke-Hartlieb, S., Rothkegel, M., Bartsch, J. W., Buchmeier, S., Jockusch, B. M., and Jockusch, H. (1999). A role for polyproline motifs in the spinal muscular atrophy protein SMN. Profilins bind to and colocalize with smn in nuclear gems. J Biol Chem 274, 37908-37914
Rudiger, M., Jockusch, B. M., and Rothkegel, M. (1997). Epitope tag-antibody combination useful for the detection of protein expression in prokaryotic and eukaryotic cells. Biotechniques 23, 96-97.
Schluter, K., Jockusch, B. M., and Rothkegel, M. (1997). Profilins as regulators of actin dynamics. Biochim Biophys Acta 1359, 97-109.
Rothkegel, M., Mayboroda, O., Rohde, M., Wucherpfennig, C., Valenta, R., and Jockusch, B. M. (1996). Plant and animal profilins are functionally equivalent and stabilize microfilaments in living animal cells. J Cell Sci 109, 83-90
Jockusch, B. M., Bubeck, P., Giehl, K., Kroemker, M., Moschner, J., Rothkegel, M., Rudiger, M., Schluter, K., Stanke, G., and Winkler, J. (1995). The molecular architecture of focal adhesions. Ann Rev Cell Dev Biol 11, 379-416.
Giehl, K., Valenta, R., Rothkegel, M., Ronsiek, M., Mannherz, H. G., and Jockusch, B. M. (1994). Interaction of plant profilin with mammalian actin. Eur J Biochem 226, 681-689.