Promotionsvorhaben

The fight against multi-resistant strains of bacteria is an issue of global importance. The development of alternative classes of compounds found…

The development of computational models to predict the biological activity of small molecules has become an important part of modern drug discovery.…

Polyprenylated xanthones are natural products which are found in various Hypericum species. The prenylation of the core structure which is catalyzed…

Pseudomonas aeruginosa is an opportunistic bacterium that causes severe nosocomial infections and chronic infections in cystic fibrosis patients. This…

The goal of this project is to identify the molecular targets of antiinfectives with potent activity in phenotypic biological assays. Because many of…

Some microorganisms, for example mycobacteria, are able to prevent their degradation after being phagocytosed by macrophages. Since many antibiotics…

Developing novel antiinfectives requires a detailed understanding of the chemical interactions between drug molecules and their biological target.…

My research focus is the analysis of metabolomics data. It includes the analysis of untargeted metabolomics and targeted metabolomics of diseases. The…

The medicinal mushroom Hericium Erinaceus is known to produce secondary metabolites with neurotrophin-inducing properties. One of those secondary…

Multi-resistant infectious agents are a growing problem in everyday clinical life and are threatening the health of the population even in countries…