Selected Publications

Stempel M, Maier O, Mhlekude B, Drakesmith H, Brinkmann MM. Novel role of bone morphogenetic protein 9 in innate host responses to HCMV infection. EMBO Rep. Mar 2024. 25(3):1106-1129. (» DOI: 10.1038/s44319-024-00072-2). PDF

Eberhage J, Bresch IP, Ramani R, Viohl N, Buchta T, Rehfeld CL, Hinse P, Reubold TF, Brinkmann MM, Eschenburg S. Crystal structure of the tegument protein UL82 (pp71) from human cytomegalovirus. Protein Sci. Mar 2024. 33(3):e4915. (» DOI: 10.1002/pro.4915). PDF

Schwanke H, Gonçalves Magalhães V, Schmelz S, Wyler E, Hennig T, Günther T, Grundhoff A, Dölken L, Landthaler M, van Ham M, Jänsch L, Büssow K, van den Heuvel J, Blankenfeldt W, Friedel CC, Erhard F, Brinkmann MM. The cytomegalovirus M35 protein directly binds to the interferon-β enhancer and modulates transcription of Ifnb1 and other IRF3-driven genes. J Virol. Jun 2023. 97(6):e0040023. (» DOI: 10.1128/jvi.00400-23). PDF

González-Pérez AC, Stempel M, Wyler E, Urban C, Piras A, Hennig T, Ganskih S, Wei Y, Heim A, Landthaler M, Pichlmair A, Dölken L, Munschauer M, Erhard F, Brinkmann MM. The zinc finger antiviral protein 1 ZAP restricts human cytomegalovirus and selectively binds and destabilises viral UL4/UL5 transcripts. mBio. Mai 2021. 12:e02683-20. (» DOI: 10.1128/mBio.02683-20). PDF

Schwanke H, Stempel M, Brinkmann MM. Of Keeping and Tipping the Balance: Host Regulation and Viral Modulation of IRF3-Dependent IFNB1 Expression. Viruses. Jul 2020. 12:733. (» DOI: 10.3390/v12070733). PDF

Fabits M, Gonçalves Magalhães V, Chan B, Girault V, Elbasani E, Rossetti E, Saeland E, Messerle M, Pichlmair A, Juranić Lisnić V, Brinkmann MM. The Cytomegalovirus Tegument Protein UL35 Antagonizes Pattern Recognition Receptor-Mediated Type I IFN Transcription. Microorganisms. Mai 2020. 8:790. (» DOI: 10.3390/microorganisms8060790). PDF

Reimer E, Stempel M, Chan B, Bley H, Brinkmann MM. Protein tyrosine phosphatase 1B is involved in efficient type I interferon secretion upon viral infection. Journal of Cell Science. Apr 2020. 134:jcs246421. (» DOI: 10.1242/jcs.246421). PDF

González-Pérez AC, Stempel M, Chan B, Brinkmann MM. One Step Ahead: Herpesviruses Light the Way to Understanding Interferon-Stimulated Genes (ISGs). Frontiers in Microbiology. Feb 2020. 11:124. (» DOI: 10.3389/fmicb.2020.00124). PDF

Stempel M, Chan B, Brinkmann MM. Coevolution pays off: Herpesviruses have the license to escape the DNA sensing pathway. Med Microbiol and Immunol. Aug 2019. 208: 495. (» DOI: 10.1007/s00430-019-00582-0). PDF

Stempel M, Chan B, Juranić Lisnić V, Krmpotić A, Hartung J, Paludan SR, Füllbrunn N, Lemmermann NA, Brinkmann MM. The herpesviral antagonist m152 reveals differential activation of STING-dependent IRF and NF-κB signaling and STING's dual role during MCMV infection. EMBO J. Mar 2019. 38:e100983. (» DOI: 10.15252/embj.2018100983). PDF

Bussey KA, Murthy S, Reimer E, Chan B, Hatesuer B, Schughart K, Glaunsinger B, Adler H, Brinkmann MM. Endosomal Toll-Like Receptors 7 and 9 Cooperate in Detection of Murine Gammaherpesvirus 68 Infection. J Virol. Jan 2019. 93:e01173-18. (» DOI: 10.1128/JVI.01173-18). PDF

Bussey KA, Lau U, Schumann S, Gallo A, Osbelt L, Stempel M, Arnold C, Wissing J, Gad HH, Hartmann R, Brune W, Jänsch L, Whitehouse A, Brinkmann MM. The interferon-stimulated gene product oligoadenylate synthetase- like protein enhances replication of Kaposi's sarcoma-associated herpesvirus (KSHV) and interacts with the KSHV ORF20 protein. PLoS Pathog. Mar 2018. 14:e1006937. eCollection Mar 2018. (» DOI: 10.1371/journal.ppat.1006937). PDF

Chan B, Gonçalves Magalhães V, Lemmermann NAW, Juranić Lisnić V, Stempel M, Bussey KA, Reimer E, Podlech J, Lienenklaus S, Reddehase MJ, Jonjić S, Brinkmann MM. The murine cytomegalovirus M35 protein antagonizes type I IFN induction downstream of pattern recognition receptors by targeting NF-κB mediated transcription. PLoS Pathog. May 2017. 13:e1006382. eCollection May 2017. (» DOI:10.1371/journal.ppat.1006382). PDF

A complete list of publications can be found » here.