Publications

  • Andrée-Busch N, Eckert D, Zock-Emmenthal S and Käufer NF.: Safeguarding of pre-mRNA splicing by Prp4 kinase is based on formation of transient structures. Trends in Cell & Molecular Biology (2018) 13: 57-66. PDF (external link)
  • Andrée N, Eckert D and Käufer NF.: Prp4 kinase as part of a safeguarding mechanism during intron recognition in fungi. Endocytobiosis and Cell Research (2016) 27(4):27-38. PDF (external link)
  • Eckert D, Andrée N, Razanau A, Zock-Emmenthal S, Lützelberger M, Plath S, Schmidt H, Guerra-Moreno A, Cozzuto L, Ayté J, Käufer NF.: Prp4 Kinase Grants the License to Splice: Control of Weak Splice Sites during Spliceosome Activation. PLoS Genet. (2016) 12(1):e1005768. doi: 10.1371/journal.pgen.1005768. PDF (external link)
  • Lützelberger M. and Käufer N.F.: The Prp4 Kinase: Its Substrates, Function and Regulation in pre-mRNA Splicing (2012). http://www.intechopen.com/articles/show/title/the-prp4-kinase-its-substrates-function-and-regulation-in-pre-mrna-splicing
  • Rojas DA, Moreira-Ramos S, Zock-Emmenthal S, Urbina F, Contreras-Levicoy J, Käufer NF, Maldonado E.: Rrn7 protein, an RNA polymerase I transcription factor, is required for RNA polymerase II-dependent transcription directed by core promoters with a HomolD box sequence. J Biol Chem. (2011) 286(30):26480-6. doi: 10.1074/jbc.M111.224337. PDF (external link)
  • Lützelberger M., Bottner C.A., Schwelnus W., Zock-Emmenthal S., Razanau A., Käufer N.F.: The N-terminus of Prp1 (Prp6/U5-102K) is essential for spliceosome activation in vivo. Nucleic Acids Res. (2010) 22, 1-13. PDF (external link)
  • Newo A. N., Lützelberger M., Bottner C. A., Wehland J., Wissing J., Jänsch L., Käufer N. F.: Proteomic analysis of the U1 snRNP of Schizosaccharomyces pombe reveals three essential organism-specific proteins. Nucleic Acids Res. (2007) 35, 1391-401. PDF (external link)
  • Schwecke T., Göttling K., Durek P., Dueñas I., Käufer N.F., Zock-Emmenthal S., Staub E., Neuhof T., Dieckmann R., von Döhren H.: Nonribosomal peptide synthesis in Schizosaccharomyces pombe and the architectures of ferrichrome-type siderophore synthetases in fungi. Chembiochem. (2006) 7, 612-22. PDF (external link)
  • Bottner, C.A., Schmidt, H., Michele, M., Käufer, N.F.: Multiple genetic and biochemical interactions of Brr2, Prp8, Prp31, Prp1 and Prp4 kinase suggest a function in the control of the activation of spliceosomes in Schizosaccharomyces pombe. Curr. Genet. (2005) 48, 151-161. PDF (external link)
  • Kuhn, A. N. and Käufer, N. F.: Pre-mRNA splicing in Schizosaccharomyces pombe. Curr. Genet. (2003) 42, 241-251. PDF (external link)
  • Richert, K., Schmidt, H., Gross, T. and Käufer, N. F.: The deubiquitinating enzyme Ubp21p of fission yeast stabilizes a mutant form of protein kinase Prp4p. Mol. Genet. Genomics (2002) 267, 88-95. PDF (external link)
  • Tang Z, Käufer NF, Lin RJ. Interactions between two fission yeast serine/arginine-rich proteins and their modulation by phosphorylation. Biochem J. (2002) 368(Pt 2), 527-34. PDF (external link)
  • Schwelnus, W., Richert, K., Opitz, F., Gross, T., Habara, Y., Tani, T. and Käufer, N. F.: Fission yeast Prp4p kinase regulates pre-mRNA splicing by phosphorylating a non-SR-splicing factor. EMBO reports (2001) 2, 35-41. PDF (external link)
  • Käufer, N. F. and Potashkin, J.: Analysis of the splicing machinery in fission yeast: a comparison with budding yeast and mammals. Nucleic Acids Res. (2000) 28: 3003-3010. PDF (external link)
  • Lützelberger, M., Gross, T., and Käufer, N. F.: Srp2, a SR protein family member of fission yeast-in vivo characterization of its modular domains. Nucleic Acids Res. (1999) 27: 2618-2626. PDF (external link)
  • Schmidt, H., Richert, K., Drakas, R. A., and Käufer, N. F.: ssp42, identified as a classical suppressor of prp4-73, which encodes a kinase involved in pre-mRNA splicing in fission yeast, is a homologue of the splicing factor Prp8p. Genetics (1999) 153: 1183-1191. PDF (external link)
  • Gross, T., Käufer N. F.: Cytoplasmic ribosomal protein genes of the fission yeast Schizosaccharomyces pombe display a unique promoter type: a suggestion for nomenclature of cytoplasmic ribosomal proteins in databases. Nucleic Acids Res. (1998) 26, 3319-3322. PDF (external link)
  • Gross, T., Richert, K., Mierke, C., Lützelberger, M., and Käufer N. F.: Identification and characterization of srp1, a gene of fission yeast encoding a RNA binding domain and a RS domain typical of SR splicing factors. Nucleic Acids Res. (1998) 26, 505-511. PDF (external link)
  • Gross, T., Lützelberger, M., Wiegmann, H., Klingenhoff, A., Shenoy, S., and Käufer N. F.: Functional analysis of the fission yeast Prp4 protein kinase involved in pre-mRNA splicing and isolation of a putative mammalian homologue. Nucleic Acids Res. (1997) 25, 1028-1035. PDF (external link)
  • Witt, I., Kwart, M., Gross, T., and Käufer, N. F.: The tandem repeat AGGGTAGGGT is in the fission yeast a proximal activation sequence and activates basal transcription mediated by the sequence TGTGACTG. Nucleic Acids Res. (1995) 23, 4296-4302. PDF (external link)
  • Alahari, S. K., Schmidt, H., and Käufer, N. F.: The fission yeast prp4+ gene involved in pre-mRNA splicing codes for a predicted serine/threonine kinase and is essential for growth. Nucleic Acids Res. (1993) 21, 4079-4083. PDF (external link)
  • Witt, I., Straub, N., Käufer, N. F. and Gross, T.: The CAGTCACA box in the fission yeast Schizosaccharomyces pombe functions like a TATA element and binds a novel factor. EMBO J. (1993) 12, 1201-1208. PDF (external link)
  • Rosenberg , G. H, Alahari, S. K. and Käufer, N. F.: Prp4 from Schizosaccharomyces pombe defective in pre-mRNA splicing, isolated using genes containing artificial introns. Mol. Gen. Genet. (1991) 226, 305-309.
  • Gatermann, K. B., Hoffmann, A., Rosenberg, G. H. and Käufer, N. F.: Introduction of functional artificial introns into the naturally intronless ura4 gene of Schizosaccharomyces pombe. Mol. Cell. Biol (1989) 9, 1526-1535. PDF (external link)
  • Käufer, N. F., Simanis, V. and Nurse, P.: The fission yeast Schizosaccharomyces pombe excises a mammalian RNA transcript intervening sequence. Nature (1985) 318, 78-80.