Reliable simulations of flow separation on airfoils, wings and powered engine nacelles at high Reynolds numbers represent great challenges in defining suitable mathematical models, computing numerically accurate solutions and providing comprehensive experimental data for the validation of numerical simulations. Additional scientific problems arise from the need to consider airframe-engine interactions and inhomogeneous onset flow conditions as real aircraft operate in atmospheric environments with sometimes rather large distortions. The symposium aims to bring together scientists dealing with numerical simulations of these flows and researchers who contribute experimental work for validation.