In planktonic cultures, Shewanella putrefaciens CN-32 employs a bet-hedging strategy with respect to flagella-mediated motility: A subpopulation of the cells elaborates a secondary flagellar system in addition to the single polar system. In the proposed studies, we will determine how such a second flagellar system affects the swimming and navigation performance of the cells. In addition, we will identify the regulatory networks required to establish the heterogeneity in the population.
References:
- List of publications (K. Thormann)
Contact details:
Prof. Dr. Kai Thormann
Institute for Microbiology and Molecular Biology
Justus Liebig University Giessen
Heinrich-Buff-Ring 26-32
D-35392 Giessen
Germany
Tel.: +49-(0)641 99-35545
Fax.: +49-(0)641 99-35549
Kai.Thormann(at)mikro.bio.uni-giessen.de
Homepage Link
Co-workers:
Student working on the project: Dipl. Biol. Florian Roßmann
Collaboration with Prof. Dr. Victor Sourjik, University of Heidelberg
Chemotaxis with two flagellar systems, modeling of swimming patterns
References:
Thormann
Nanda, A. M., Thormann, K. M. and Frunzke, J. (2015) Impact of spontaneous prophage induction on the fitness of bacterial populations and host-microbe interactions. J. Bacteriol., 197, 410-419.
Schuhmacher, J. S., Rossmann, F., Dempwolff, F., Knauer, C., Altegoer, F., Steinchen, W., Dörrich, A. K., Klingl, A., Stephan, M., Linne, U., Thormann, K. M. and Bange, G. (2015) MinD-like ATPase FlhG effects location and number of bacterial flagella during C-ring assembly. Proc. Natl. Acad. Sci. U.S.A., 112, 3092-3097.
Bubendorfer, S., Koltai, M., Rossmann, F., Sourjik, V. and Thormann, K. M. (2014) Secondary bacterial flagellar system improves bacterial spreading by increasing the directional persistence of swimming. Proc. Natl. Acad. Sci. U.S.A., 111, 11485-11490.
Bubendorfer, S., Held, S., Windel, N., Paulick, A., Klingl, A. and Thormann, K. M. (2012) Specificity of motor components in the dual flagellar system of Shewanella putrefaciens CN-32. Mol. Microbiol., 83, 335-350.
Koerdt, A., Paulick, A., Mock, M., Jost, K. and Thormann, K. M. (2009) MotX and MotY are required for flagellar rotation in Shewanella oneidensis MR-1. J. Bacteriol., 191, 5085-5093.
Paulick, A., Koerdt, A., Lassak, J., Huntley, S., Wilms, I., Narberhaus, F. and Thormann, K. M. (2009) Two different stator systems drive a single polar flagellum in Shewanella oneidensis MR-1. Mol. Microbiol., 71, 836-850.