TU Braunschweig's six faculties and more than 120 institutes support numerous research projects which examine a broad range of topics. Special emphasis is placed on Collaborative Research Centres, Research Units and Priority Programmes sponsored by the DFG (Deutsche Forschungsgemeinschaft), Germany's central self-governing research funding organisation.
Colaborative Research Centres comprise long-term research projects. They are often interdisciplinary research institutions of a university and are funded for up to 12 years. Scientists from other universities or research institutions may be involved in Collaborative Research Centres.
The SFB/Transregio 277 (TRR 277) aims to comprehensively investigate additive manufacturing (AM) in interdisciplinary basic research as a novel digital manufacturing technology in construction and thus to create the framework conditions for its introduction in the construction industry. Additive manufacturing is fundamentally different from conventional predominantly manual manufacturing technologies in construction, which are designed for low labor costs but not for material-efficient construction. As the construction industry is one of the world's largest emitters of CO2, the highly efficient use of resources in construction is of global societal importance. In this interdisciplinary, cross-location research project, the two universities TU Braunschweig and TU Munich are pursuing a novel manufacturing approach for the construction industry, using additive manufacturing to use material only where it fulfills a function. This will pave the way for a new freedom of design in the construction industry while at the same time enabling the resource-efficient use of building materials.
The work program of TRR 277 focuses on the two research approaches: Material and process combination and end-to-end digitalization in the construction industry.
TU Braunschweig: Institute of Mechanics and Adaptronics (IMA), Institute of Applied Mechanics (IAM), Institute of Building Materials, Concrete Construction and Fire Safety (iBMB), Institute for Construction Engineering and Management (IBB), Institute of Machine Tools and Production Technology (IWF), Institute of Joining and Welding (ifs), Institute of Geodesy and Photogrammetry (IGP), Institute for Particle Technology (iPAT), Institute for computational modeling in civil engineering (iRIMB), Institute of Steel Structures (IS), Institute of Structural Design (ITE)
TU Munich: TT Professorship Digital Fabrication (DF), Chair of Architectural Informatics (AI), Chair for Computation in Engineering (CiE), The Chair of Computational Modeling and Simulation (CMS), Chair of Materials Handling, Material Flow, Logistics (fml), Chair of Building Technology and Climate Responsive Design (BT), Chair of Timber Structures and Building Construction (HBB), Chair of Metal Structures (MB), Chair of Structural Analysis (st), Chair of Materials Science and Testing (cbm), Institute for Machine Tools and Industrial Management (iwb), Professur für Technikdidaktik (edu)
Wilhelm-Klauditz-Institut (WKI): Fraunhofer Institute for Wood Research
Leibniz University Hannover: Institute for Assembly Technology (match)
With the major goal of climate-neutral flying, we are conducting research on potentials and synergies through highly integrated aircraft development in numerous sub-projects at TU Braunschweig, University of Stuttgart, LUH Hannover and DLR Braunschweig in the new transregio SynTrac collaborative research centre. We use interactions of the disciplines aerodynamics, acoustics, flight physics, structural mechanics and thermodynamics through a multidisciplinary, cross-system view of the aircraft development process to develop future highly efficient aircraft through innovative approaches.
TU Braunschweig: Institute for Acoustics (InA), Institute of Jet propulsion and Turbomachinery (IFAS), Institute of Flight Guidance (IFF), Institute of Aircraft Design and Lightweight Structures (IFL), Institute of Mechanics and Adaptronics (IMA), Institute of Fluid Mechanics (ISM)
University of Stuttgart: Institute of Aerodynamics and Gas Dynamics (IAG), Institute of Flight Mechanics and Control (IFR), Institute of Aircraft Design (IFB), Institute of Aircraft Propulsion Systems (ILA), Institute of Structural Mechanics and Dynamics in Aerospace Engineering (ISD), Institute of Aerospace Thermodynamics (ITLR)
Deutsches Zentrum für Luft- und Raumfahrt / German Aerospace Center (DLR): Institute of Aerodynamics and Flow Technology (AS)
Leibniz University Hannover: Institute of Electric Power Systems (IfES)
The CRC 1143 is devoted to the study of a class of magnets where competing (frustrated) interactions prevent the establishment of a simple conventionally ordered state, leading to a plethora of alternative and highly non-trivial behaviors, the most remarkable of which involve either topological phases of matter or proximity to them. The CRC aims to identify, produce, and understand magnetic materials exhibiting these.To do so, it bundles requisite expertise for an integrated research program, comprising intuitive and machine-based searches for new and promising chemical compounds; capabilities of synthesizing and characterizing these compounds as well as studying their physical properties experimentally; and finally modeling and analyzing the experiments in order to synthesize the results into a deeper understanding of the field which we call correlated magnetism.
Contact at TU Braunschweig: Prof. Wolfram Brening – Institute for Theoretical Physics
Participating Institutes of TU Braunschweig: Institute for Theoretical Physics
The SFB is coordinated by the Technical University of Dresden.
In the CRC 298, a fundamentally new approach to implant research is being pursued via the synergistic and integrative collaboration of scientists from a wide range of disciplines. Through the scientific use of safety-relevant concepts from the engineering sciences, smart implant systems will be developed which for the first time enable continuous monitoring for the early detection of implant complications and, accordingly, allow a response to restore the initial status. By developing chemical, biological or physical detection systems, early detection of technical or biological complications will be facilitated and transmitted, either externally to the physician or internally to autonomous implant-associated systems. Following detection, reactions are triggered, which promote technical or biological regeneration. The new detection and reac-tion systems and the co-generated data will converge into an implant lifecycle management system and lead to increased implant and patient safety in the long term. As physician-patient interactions will be crucial for improving implant safety and sustainable treatment success, communication research will provide an innovative contribution to this process.
Contact at TU Braunschweig: Prof. Henning Menzel – Institute of Technical Chemistry
Participating Institutes of TU Braunschweig: Institute of Technical Chemistry
The SFB is coordinated by the Hannover Medical School.
The CRC 1454 brings together the transdisciplinary expertise from three faculties of the University of Bonn (Medicine, Mathematics and Natural Sciences, and Philosophy), the German Center for Neurodegenerative Diseases, the Max-Planck-Institute for Metabolism Research in Cologne, and the Braunschweig Integrated Centre of Systems Biology to collaboratively address the unmet need to understand the mechanisms leading to metaflammation and to translate these findings into novel therapeutic and preventative strategies. The CRC aims to i. study how the triggers associated with a Western lifestyle lead to immune cell programming and cause metaflammation, ii. investigate the crosstalk between reprogrammed immune cells and the inflamed tissues, iii. address the role of specific pathways activated in metaflammation for disease pathogenesis, iv. perform bi-directional translational research between murine and human studies by investigating the discovered mechanisms in patient populations as well as in the longitudinal population ‘Rhineland Study’.
Contact at TU Braunschweig: Prof. Karsten Hiller – Institute for Biochemistry, Biotechnology and Bioformatics
Participating Institutes of TU Braunschweig: Institute for Biochemistry, Biotechnology and Bioformatics
The SFB is coordinated by the University of Bonn.
Research Units at TU Braunschweig
The Deutsche Forschungsgemeinschaft (DFG) funds research groups of outstanding scientists within the framework of DFG Research Units. The researchers work together on a specific research task. Research groups are funded for up to eight years.
FOR 2863 addresses the grand challenge of metrology in THz communication measurements systematically, and in four distinct areas: (i) Traceability to the International System of Units (SI), (ii) Characterization of the measurement system itself, (iii) Metrological characterization of the RF components and the propagation channel, (iv) Measurements required for enabling the functionality of THz communications.
The continued aim of the Research Unit FOR3022 is to gain a profound understanding of an integrated semi-autonomous Structural Health Monitoring (SHM) in Fibre Metal Laminates (FML) using guided ultrasonic waves (GUW) taking into account methods of machine learning. This requires an integral view on the physical phenomena of wave propagation even under complex environmental conditions, their interaction with hidden damage, recording of these interactions using microtechnical sensors at the location of event, and a signal processing for full damage diagnostics. The findings will be useful for the consideration and comprehensive understanding of wave propagation in all layered material systems made from components of large impedance differences.
FOR 5200 studies the dedicated strategies employed by newly infecting DNA viruses to disrupt, evade, or exploit nuclear gene expression networks to achieve the desired infection outcome. The central hypothesis is that such viral strategies may vary depending on the specific nuclear environment and state of the host cell.
The Research Unit FOR 2285 was established in 2015 to investigate debris disks - belts of comets, asteroids, and their dust around mainsequence stars. During the first phase, we carried out analytic and numerical modeling of their collisional and dynamical evolution. In parallel, we conducted impact experiments to simulate collisional processes and performed laboratory studies of the optical properties of dust and its interaction with stellar radiation. Combining the theoretical and laboratory results, we have produced detailed models that explain the observations of individual disk systems and explored statistics over larger samples, giving us new insights into a variety of puzzles including the origin of debris discs and the composition of their dust.
Contact at TU Braunschweig: Prof. Jürgen Blum – Institute of Geophysics and Extraterrestrial Physics
Participating Institutes ofTU Braunschweig: Institute of Geophysics and Extraterrestrial Physics
The main goals of FOR 2895 are the comprehensive investigation of the unresolved physical issues in the high-speed stall of transport aircraft, the extension and qualification of numerical methods for this application and the modelling of unsteady flow and nonlinear aerodynamics with reduced order models. The local physical mechanisms and interactions must be understood to achieve a description of the aerodynamic effects for the complete configuration. The knowledge gain will be achieved by coordinated numerical and experimental studies of the flow physics in different parts of the flow field combined with corresponding investigations on a full aircraft configuration.
Contact at TU Braunschweig: Prof. Rolf Radespiel – Institute of Fluid Mechanics
Participating Institutes at TU Braunschweig: Institute of Fluid Mechanics
FOR 3004 brings together clinician scientists in the field of antibody-mediated immunological disorders with basic scientists in the field of neurophysiology, molecular neurobiology, and neuroimmunology collectively investigating autoantibody-mediated pathology in the CNS. The aim of the Research Unit is to elucidate the pathophysiology of autoimmune encephalitis in which autoantibodies are directed at synaptic targets.
Contact at TU Braunschweig:Prof. Michael Hust – Institute of Biochemistry, Biotechnology and Bioinformatics
Participating Institutes at TU Braunschweig: Institute of Biochemistry, Biotechnology and Bioinformatics
The project investigates adaptation and change in individual language-contact situations, i.e. bilingual language processing. It tests whether psycholinguistic adaptation to changes in input may be the seedbed of historical change, as individual adaptation translates into different output, which, in turn, provides changes in input to speakers and language learners.Specifically, the project examines (a) if bilinguals adapt in the same way as native speakers and (b) if adaptation to the L2 spills over into the L1. This project studies adaptation in the context of the dative alternation, examining adaptation to frequency biases in the input and grammatical constraints on adaptation in different groups of monolingual and bilingual native speakers as well as late L2 learners of English.
Cytochalasans are natural products produced by fungi which have many potent biological activities. They bind strongly to actin and thus significantly effect eukaryotic cells. They also display remarkable bioactivities in prokaryotes and as anti-viral compounds where actin cannot be the target. They inhibit protein synthesis, sugar transport, plant growth, tumor necrosis factor and angiogenesis and are involved in immunosuppression and virulence and avirulence of fungi towards plants and insects, although most molecular mechanisms underlying these processes are unknown. Cytochalasans are constructed from amino acids and polyketides and they are often oxidatively tailored. Many hundreds of family members are known, but very few systematic investigations of structure activity relationships have been reported because very few cytochalasans are commercially available. The proposed CytoLabs Research Unit aims to address these problems through a systematic and integrated collaborative project between groups with expertise in the discovery, chemical synthesis, bioengineering, cell biology, in vivo and in vitro biochemistry, in planta and ecological bioactivity of cytochalasans. It aims to be able to apply modern synthetic chemistry (Kalesse, Klahn) and synthetic biology (Cox) to rapidly create known and new cytochalasans.
In the frame of the priority program SPP 1934 “Dispersity, structure and phase changes of proteins and bio agglomerates in biotechnological processes” the stressing of sensitive proteins and bio agglomerates by the process environment during fermentation, down-stream processing and formulation is investigated. The priority program is addressed to scientists working in the fields of chemical and process engineering, especially particle technology and biochemical engineering, as well as of biology. These research fields are connected today not strongly enough. Therefore, in the priority program these research fields are cross-linked intensively.
Research Training Groups are established by universities to promote early career researchers. They are funded by the DFG for a period of up to nine years. Their key emphasis is on the qualification of doctoral researchers within the framework of a focused research programme and a structured training strategy.
CircularLIB is a training group on the circular production and usage of lithium-ion batteries. The three universities, TU Braunschweig, TU Clausthal and the Leibnitz University of Hannover together with the Fraunhofer Institute for Surface Engineering and Thin Films IST cooperate in this program.
The RTG focuses on methods in three fields of nanometrology: complex measurands with multiparametric interdependencies, complex measurands in biological nanosystems, and measurands based on quantum effects determine the scientific training programme. This interdisciplinary approach will lead to a better understanding and application of general strategies to achieve traceability of novel measurands emerging in complex nanosystems.
Contact at TU Braunschweig: Prof. Meinhard Schilling – Institute for Electrical Measurement Science and Fundamental Electrical Engineering
The fundamental goal of the research programme is the development of scientific approaches to describe and to evaluate the evolution of properties and quality of buildings and infrastructures with respect to physical and chemical induced degradation. The multi-coupled pro cesses are described by modeling equations on different spatial and temporal scales based on the theory of continuum mechanics and the theory of porous media. The developed models will serve as a basis for prognoses of the development of building materials and structures by means of advanced simulations validated by experimental data. The multi-scale models to be developed describe the different phenomena of aging as a coupled process, typically requiring a direct coupling of the individual processes in space and time, in order to appropriately the interaction of processes and to integrate all information for an evaluation of the quality of buildings. In an extension of the current approaches on the macroscopical scale, the mechanisms of transport as well as physical and chemical damage shall be investigated experimentally and shall be modelled on different scales of materials and buildings.
Contact at TU Braunschweig: Prof. Manfred Krafczyk – Institute for computational modeling in civil engineering
Severe illness caused by viral pathogens constitutes a constant threat to the human society, either as acute epidemics with dramatic consequences or as chronic viral infections in individuals with an increased susceptibility, e.g., due to a compromised immune system. The development of efficient antiviral intervention strategies can be reduced to two steps: 1) a profound understanding of an essential process within the viral life cycle and 2) the capitalization on this knowledge to devise novel antiviral strategies. Recent virology research has revealed the urgent need to extend our understanding to the mechanistic level, i.e., how viral proteins and protein complexes exert their functions within the host cell.
We therefore propose a cross-disciplinary research training group with three key aims:
To instruct a new generation of scientists in how to address future challenges in virology research at the interface between virology and structural biology by applying cross-disciplinary, multi-resolution techniques.
To further develop integrative methods that bridge different resolution scales in virology.
To apply these interdisciplinary approaches to challenging virological questions that pave the way for the development of novel antiviral intervention strategies
Drag reduction by laminarisation of aircraft boundary layers is among the most promising technological approaches to achieve long-term objectives for fuel-efficient and sustainable commercial aviation. While smaller short-range aircraft with relatively low Reynolds numbers and flight speeds can take advantage of designs with natural laminar flow, one has to employ active flow control by local suction to achieve laminar boundary layers at higher Reynolds numbers and at aircraft components with large sweep angles, as used for higher cruise speeds.
Contact: Prof. Dr.-Ing. Rolf Radespiel - Institut für Strömungsmechanik
Involved Project Partners: Institute of Fluid Mechanics, TU Braunschweig, and German-Dutch Wind Tunnels, The Netherlands.