Product structures

Simulation of distributed product structures in combined discrete and continuous production processes for solid, particulate products

Contact person: Ann Kathrin Schomberg

Summary of the overall project:

In the context of the production of pharmaceutical drugs this project deals with modelling and simulation of the production of solid particulate products using the example of tablets. Product quality is influenced by the interlinking of production process steps which affect the structures and properties of the intermediate and end products. In addition to fluctuating ambient conditions, the process parameters used have a varying influence on the distributed properties of the materials, which can also be of varying degrees. Knowledge of the existing product quality of the intermediate and end products is of central importance in pharmaceutical production. The aim of the project is the agent-based simulation of product structures across the interlinked process steps. The project focuses on the process steps of mixing and tableting, for whose sub-processes process models are developed and extended, so distributed product properties can be processed and mapped. The individual process models will then be integrated into a process chain model. The aim of the simulation is to increase the transparency of the process and improve the traceability of product properties within the process. An associated optimized forward and backward process control is investigated within the project. The project is funded by the DFG and is carried out in cooperation with the Institute for Machine Tools and Manufacturing Engineering (Institut für Werkzeugmaschinen und Fertigungstechnik, IWF).