In the SYPHY project, TLK-Thermo GmbH and the Technical University of Braunschweig are developing methods and models for flexible hydrogen refueling stations with reduced system complexity, minimized electrical power requirements, and cyber-physical operating strategies. The focus is on a software library for the model-based design, optimization, and operation of various refueling station concepts. TLK-Thermo GmbH is developing physically grounded, validated, and real-time-capable models as well as optimization methods for this purpose, while the Technical University of Braunschweig is investigating innovative pre-cooling systems and operational strategies to reduce power consumption and improve operational flexibility.