Total synthesis and biological activity of marine natural products, chemistry of biogenetic key molecules, development of new chemistry-based methods for Chemical Biology, computer-assisted structure elucidation.
Chemistry of communication, chemical ecology and natural products chemistry using organic synthesis, analysis, and biosynthesis to decipher compound structures and function.
Development and application of elegant and efficient synthetic and catalytic methods, and (total) syntheses of larger natural and non-natural products (e.g. in the field of carbohydrates, glycolipids, nucleosides and novel types of fluorescent dyes).
Development of antimicrobial and anticancer, extracellular-targeted drug-conjugates, semi- and total synthesis of bioactive natural products and development of bio responsive linker- and reporter molecules.
Development and application of new tools in computational chemistry, in silico simulation of molecular recognition, studies on mechanochemistry and bonding theory.