TU BRAUNSCHWEIG

PUBMED: 30912268
Timmis, K.N., Cavicchioli, R., Garcia, J.L., Nogales, B., Chavarría, M., Stein, L., McGenity, T.J., Webster, N., Singh, B., Handelsman, J., de Lorenzo, V., Pruzzo, C., Timmis, J., Ramos Martín, J.L., Verstraete, W., Jetten, M., Danchin, A., Huang, W., Gilbert, J., Lal, R., Santos, H., Sang, S.Y., Sessitsch, A., Bonfante, P., Gram, L., Lin, R.T.P., Ron, E., Karahan, C., van der Meer, J.R., Artunkal, S., Jahn, D. & Harper, L. (2019)
The urgent need for microbiology literacy in society

Environ. Microbiol. 21:1513-1528


PUBMED: PMC6459899
Ünal, C. M., Karagöz, M. S., Berges, M., Priebe, C., Borrero De Acuña, J. M., Wissing, J., Jänsch, L., Jahn, D. & Steinert, M. (2019)
Pleiotropic Clostridioides difficile cyclophilin PpiB controls cysteine-tolerance, toxin production, the central metabolism and multiple stress responses

Front. Pharmacol. 10:340

PUBMED: 30835726
Münch, K., Münch, R., Biedendieck, R., Jahn, D. & Müller, J. (2019)
Evolutionary model for the unequal segregation of high copy plasmids

PLOS Comp. Biol., 15:e1006724


PUBMED: 30608141
Blaženović, I., Kind, T., Sa, M., Ji, J., Vaniya, A., Wancewicz, B., Roberts, B., Torbasinovic, H., Lee, T., Mehta, S., Showalter, M., Song, H., Kwok, J., Jahn, D., Kim, J. & Fiehn, O. (2019)
Structure annotation of all mass spectra in untargeted metabolomics

Anal. Chem., 91:2155-2162


PUBMED: 30353924
Groenewald, M., Hebecker, S., Fritz, C., Czolkoss, S., Wieselmann, M., Heinz, D., Jahn, D., Narberhaus, F., Meriyem, A. & Moser, J. (2019)
Virulence of Agrobacterium tumefaciens requires Lipid Homeostasis mediated by the Lysyl-Phosphatidylglycerol Hydrolase

Mol. Microbiol., 111:269-286

PUBMED: 30828322
Neumann-Schaal, M., Jahn, D. & Schmidt-Hohagen, K. (2019)

Metabolism the difficile way - the key to the success of the pathogen Clostridioides difficile

Front. Microbiol., 10:219

PUBMED: 30619231
Berges, M. ,  Michel, A.-M., Lassek, C., , Nuss, A. M., Beckstette, M., Dersch, P., Riedel, K., Sievers, S., Becher, D., Otto, A. ,  Maaß, S., Rohde, M., Eckweiler, D., Borrero-de Acuna, J. M., Jahn, M. J., Neumann-Schaal, M. & Jahn, D. (2018)
Iron regulation in Clostridioides difficile

Front. Microbiol., 9:3183


PUBMED: 30564207
Ünal, C. M., Berges, M., Smit,N. Schiene-Fischer, C., Priebe, C., Strowig, T., Jahn, D. & Steinert, M. (2018)
PrsA2 (CD630_35000) of Clostridioides difficile is an active parvulin-type PPIase and a virulence modulator

Front. Microbiol., 9:2913


PUBMED: 30410474
Bernal, I, Hofmann, J. D., Bulitta, B., Klawonn, F., Michel, A.-M., Jahn, D., Neumann-Schaal, M., Bruder, D. & Jänsch, L. (2018)
Clostridioides difficile activates human mucosal-associated invariant T cells.

Front. Microbiol., 9:2532


PUBMED: 30186274
Hofmann, J. D., Otto, A., Berges, M., Biedendieck, R., Michel, A.-M., Becher, D., Jahn, D. & Neumann-Schaal, M. (2018)
Metabolic reprogramming of Clostridioides difficile during the stationary phase with the induction of toxin production.

Front. Microbiol., 9:1970


PUBMED: 30039521
Härtig, E., Frädrich, C., Behringer, M., Hartmann, A. , Neumann-Schaal, M. & Jahn, D. (2018)
Functional definition of the two effector binding sites, the oligomerization and DNA binding domains of the Bacillus subtilis LysR-type transcriptional regulator AlsR.

Mol. Microbiol., 109:845-864


PUBMED: 29717024
Groenewold, M., Massmig, M., Hebecker, S., Danne, L., Magnowska, Z., Nimtz, M., Narberhaus, F., Jahn, D., Heinz, D.W., Jänsch, L. & Moser, J. (2018)

A phosphatidic acid binding protein is important for lipid homeostasis and adaptation to anaerobic biofilm conditions in Pseudomonas aeruginosa.

Biochem J. 475:1885–1907


PUBMED: 29867814
Kirchhoff, C., Ebert, M., Jahn, D. & Cypionka, H. (2018)
Chemiosmotic energy conservation in Dinoroseobacter shibae: Proton translocation driven by aerobic respiration, denitrification and photosynthetic light reaction.

Front. Microbiol. 9:903


PUBMED: 29282292
Haskamp, V., Karrie, S., Mingers, T., Barthels, S., Alberge, F., Magalon, A., Müller, K., Bill, E., Lubitz, W., Kleeberg, K., Schweyen, P., Bröring, M., Jahn, M. & Jahn, D. (2018)
The radical SAM protein HemW is a heme chaperone.

J Biol Chem. 293:2558-2572

Müller, K., Mingers,  T., Haskamp, V., Jahn, D.  & Jahn, M (2018)
Biosynthesis and Insertion of Heme

in "Handbook of Hydrocarbon and Lipid Microbiology Series. Aerobic Utilization of Hydrocarbons, Oils, and Lipids" in press

PUBMED: 29136200
Eckweiler, D., Dudek, C.-A., Hartlich, J., Broetje, D. & Jahn, D. (2017)
PRODORIC2: the bacterial gene regulation database in 2018.

Nucleic Acids Res. 46:D320-D326


PUBMED: 28857512
Borrero-de Acuña, J.M., Timmis, K.N., Jahn, M. & Jahn, D. (2017)
Protein complex formation during denitrification by Pseudomonas aeruginosa.

Microb Biotechnol. 10:1523-1534


PUBMED: 28765283
Ebert, M., Schweyen, P., Bröring, M., Laass, S.,  Härtig, E. & Jahn, D. (2017)
Heme and nitric oxide binding by the transcriptional regulator DnrF from the marine bacterium Dinoroseobacter shibae increases napD promoter affinity.

J. Biol. Chem. 292:15468-15480


PUBMED: 28619474
Riedel, T., Wetzel, D., Hofmann, J.D., Plorin, S.P.E.O., Dannheim, H., Berges, M., Zimmermann, O., Bunk, B., Schober, I., Spröer, C., Liesegang, H., Jahn, D., Overmann, J., Groß, U. & Neumann-Schaal, M. (2017)
High metabolic versatility of different toxigenic and non-toxigenic Clostridioides difficile isolates

Int. J. Med. Microbiol. 307:311-320


PUBMED: 29086039
Blaženović, I., Kind, T., Torbašinović, H., Obrenović, S., Mehta, S.S., Tsugawa, H., Wermuth, T., Schauer, N., Jahn, M., Biedendieck, R., Jahn, D. & Fiehn, O. (2017)
Comprehensive comparison of in silico MS/MS fragmentation tools of the CASMI contest: database boosting is needed to achieve 93% accuracy

J. Cheminform. 9:32


PUBMED: 28473807
Ebert, M., Laass, S., Thürmer, A., Roselius L., Eckweiler, D., Daniel, R., Härtig, E. & Jahn, D. (2017)
FnrL and three Dnr regulators are used for the metabolic adaptation to low oxygen tension in Dinoroseobacter shibae.

Front. Microbiol. 8:642

Jahn, D. (2017)
Das Mikrobiom. Dein Freund und Helfer

Audi BKK Magazin-Gesundheit 02/2017, Seite 8-13


PUBMED: 28123057
Dailey, H., Dailey, T., Gerdes, S., Jahn, D., Jahn, M., O´Brian, M. & Warren, M. J. (2017)
Prokaryotic heme biosynthesis: mutiple pathways to a common essential product.

Microbiol. Mol. Biol. Rev., in press

PUBMED: 28006011
Nuss, A. M., Schuster, F., Roselius L., Klein, J., Bücker, R., Herbst, K., Heroven, A. K., Pisano, F., Wittmann, C., Münch, R., Müller, J., Jahn, D. & Dersch, P. (2016)
A precise temperature-responsive bistable switch controlling Yersinia virulence.

PLOS Pathogens, 12: e1006091


PUBMED: 27466367
Füller, J. J., Röpke, R., Krausze, J., Rennhack, K. E., Daniel, N. P., Blankenfeldt, W., Schulz, S., Jahn, D. & Moser J. (2016)
Biosynthesis of Violacein: Structure and Function of L-Tryptophan Oxidase VioA from Chromobacterium violaceum.

J. Biol. Chem., 291: 20068-20084


PUBMED: 27303368
Patzelt, D., Michael, V., Päuker, O., Ebert, M., Tielen, P., Jahn, D., Tomasch, J., Petersen, J. & Wagner-Döbler, I. (2016)
Gene flow across genus barriers - Conjugation of Dinoroseobacter shibae's 191-kb killer plasmid into Phaeobacter inhibens and AHL-mediated expression of type IV secretion systems.

Front. Microbiol., 7: 742


PUBMED: 26903416
Borrero-de Acuna, J. M., Rohde, M.,  Wissing, J., Jänsch, L.,  Schobert, M., Molinari, G.,  Timmis, K. N.,  Jahn, M. & Jahn, D. (2016)
Protein Network of the Pseudomonas aeruginosa Denitrification Apparatus,

J. Bacteriol., 198: 1401-1413


PUBMED: 26853478
Ferrer, A., Bunk, B., Spröer, C., Biedendieck, R., Valdés, N., Jahn, M., Jahn, D., Orellana, O. & Levican, G. (2016)
Complete genome sequence of the bioleaching bacterium Leptospirillum sp. group II strain CF-1.

J. Biotechnol., 222: 21-22.

Rabus, R., Engelmann, S., Jahn, D., Petersen, J., Schomburg, D., Schulz, S. & Wagner-Döbler, I. (2016)
Systembiologie der marinen Roseobacter-Gruppe,

Systembiologie, 11: 16-19

PUBMED: 26261323
Hebecker, S. , Krausze, J., Hasenkampf, T., Schneider, J., Groenewold, M., Reichelt, J., Jahn, D., Heinz, D. W. & Moser, J. (2015)
Structures of two bacterial resistance factors mediating tRNA-dependent aminoacylation of phosphatidylglycerol with lysine or alanine

Proc. Natl. Acad. Sci. USA, 112:10691-10696


PUBMED: 26170416
Borrero-de Acuña, J. M., Molinari, G., Rohde, M., Dammeyer, T., Wissing, J., Jänsch, L., Arias, S. , Jahn, M. , Schobert, M. , Timmis, K.N. & Jahn, D. (2015)
A periplasmic complex of the nitrite reductase NirS, the chaperone DnaK and the flagellum protein FliC is essential for flagellum assembly and motility in Pseudomonas aeruginosa

J Bacteriol., 197:3066-3075


PUBMED: 26216844
Rücker, N., Billig, S., Bücker, R., Jahn, D., Wittmann, C. & Bange F. C. (2015)
Acetate dissimilation and assimilation in Mycobacterium tuberculosis depend on carbon availability

J Bacteriol., 197:3182-3190


PUBMED: 26088139
Lange, C., Kiesel, S., Peters, S., Virus, S., Scheer, H., Jahn, D. & Moser, J. (2015)
Broadened Substrate Specificity of 3-Hydroxyethyl Bacteriochlorophyllide α Dehydrogenase (BchC) Indicates a New Route for the Biosynthesis of Bacteriochlorophyll α

J Biol Chem., 290:19697-19709


PUBMED: 26116677
Münch, K., Müller, J., Wienecke, S., Bergmann, S., Heyber, S., Biedendieck, R., Münch, R. & Jahn, D. (2015)
Polar fixation of plasmids during recombinant protein production in Bacillus megaterium results in population heterogeneity.

Appl Environ Microbiol., 81:5976-5986


PUBMED: 26184943
Wibberg, D., Tielen, P., Narten, M., Schobert, M., Blom, J., Schatschneider, S., Meyer, A.-K., Neubauer, R., Albersmeier, A., Albaum, S., Jahn, M., Goesmann, A., Vorhölter, F.-J., Pühler, A. & Jahn, D.  (2015)
Genome sequence of the urethral isolate Pseudomonas aeruginosa RN21

GenomeA, 3: e00788-15


PUBMED: 25776700
Zischka, M., Künne, C.T., Blom, J., Wobser, D., Sakιnç, T., Schmidt-Hohagen, K., Dabrowski, P.W., Nitsche, A., Hübner, J., Hain, T., Chakraborty, T., Linke, B., Goesmann, A., Voget, S., Daniel, R., Schomburg, D., Hauck, R., Hafez, H.M., Tielen, P., Jahn, D., Solheim, M., Sadowy, E., Larsen, J., Jensen, L.B., Ruiz-Garbajosa, P., Quiñones Pérez, D., Mikalsen, T., Bender, J., Steglich, M., Nübel, U., Witte, W. & Werner, G. (2015)
Comprehensive molecular, genomic and phenotypic analysis of a major clone of Enterococcus faecalis MLST ST40

BMC Genomics. 16:1367


PUBMED: 25673765
Lassek, C., Burghartz, M., Chaves-Moreno, D., Otto, A., Hentschker, C., Fuchs, S., Bernhardt, J., Jauregui, R., Neubauer, R., Becher, D., Pieper, D.H., Jahn, M., Jahn, D. & Riedel, K. (2015)
A Metaproteomics approach to elucidate host and pathogen protein expression during catheter-associated urinary tract infections

Mol Cell Proteomics, 14:989-1008


PUBMED: 25767242
Vorhölter, F.-J., Tielen, P., Wibberg, D., Narten, M., Schobert, M., Tüpker, R., Blom, J., Schatschneider, S., Winkler, A., Albersmeier, A., Goesmann, A., Pühler, A. & Jahn, D. (2015)
Genome Sequence of the Urethral Catheter Isolate Pseudomonas aeruginosa MH19

GenomeA, 3: e00115-15


PUBMED: 25616803
Klingner, A., Bartsch, A., Dogs, M., Wagner-Döbler, I., Jahn, D., Simon, M., Brinkhoff, T., Becker, J. & Wittmann, C. (2015)
Large-scale 13C-flux profiling reveals conservation of the Entner-Doudoroff pathway as glycolytic strategy among glucose-using marine bacteria

Appl Environ Microbiol., 81:2408-2422


PUBMED: 25422320
Kiesel, S., Wätzlich, D., Lange, C., Reijerse, E., Bröcker, M.J., Rüdiger, W., Lubitz, W., Scheer, H., Moser, J. & Jahn, D. (2015)
Iron-sulfur cluster-dependent catalysis of chlorophyllide a oxidoreductase from Roseobacter denitrificans

J Biol Chem., 290:1141-1154

Borrero-de Acuña, J.M., Jänsch, L., Rohde, M., Timmis, K.N., Jahn, D. & Jahn, M. (2015)
Interatomic characterization of protein-protein interactions in membrane associated mega-complexes

in Hydrocarbon and Lipid Microbiology Protocols, ed. Kenneth Timmis; in press


Jahn, D. (2015)
CDiff: Systembiologie, Toxine und Epidemiologie von Clostridium difficile

BIOspektrum, 05:490-492


Madigan, M.T., Martinko, J.M., Stahl, D. & Clark, D.P. (2015)
Brock Mikrobiologie kompakt

(Ed. & Hrsg. Jahn, M. & Jahn, D.) Pearson Studium, Hallbergmoos, Germany.

PUBMED: 25193818
Roselius, L., Langemann, D., Müller, J., Hense, B., Filges, S., Jahn, D. & Münch, R. (2014)
Modeling and analysis of a gene-regulatory feed-forward loop with basal expression of the second regulator

J Theoret Biol., 363:290–299


PUBMED: 24920668
Stojanovski, B. M., Hunter, G. A., Jahn, M., Jahn, D. & Ferreira, G.C. (2014)
Unstable reaction intermediates and hysteresis during the catalytic cycle of 5-aminolevulinate synthase: Implications from using pseudo and alternate substrates and a promiscuous enzyme variant

J Biol Chem., 289:22915-22925


PUBMED: 24962471
Zwerschke, D., Karrie, S., Jahn, D. & Jahn, M. (2014)
Leishmania major possesses a unique HemG-type protoporphyrinogen IX oxidase

Biosci Rep., 3:e00124


PUBMED: 24948031
Borrero-de Acuña, J.-M., Bielecka, A., Häussler, S., Schobert, M., Jahn, M., Wittmann, C., Jahn, D. & Poblete-Castro, I. (2014)
Production of medium chain length polyhydroxyalkanoate in metabolic flux optimized Pseudomonas putida

Microb Cell Fact., 13:88


PUBMED: 24648520
Laass, S., Kleist, S., Bill, N., Drueppell, K., Kossmehl, S., Woehlbrand, L., Rabus, R., Klein, J., Rohde, M., Bartsch, A., Wittmann, C., Schmidt-Hohagen, K., Tielen, P., Jahn, D. & Schomburg, D. (2014)
Gene regulatory and metabolic adaptation processes of Dinoroseobacter shibae DFL12T during oxygen depletion

J  Biol Chem, 289:13219-13231


PUBMED: 24709961
Berger, A., Dohnt, K., Tielen, P., Jahn, D., Becker, J. & Wittmann, C. (2014)
Robustness and plasticity of metabolic pathway flux among uropathogenic isolates of Pseudomonas aeruginosa.

PLoS ONE, 9:e88368


PUBMED: 24625869
Wibberg, D., Tielen, P., Blom, J., Rosin, N., Schobert, M., Tüpker, R., Schatschneider, S., Spilker, D., Albersmeier, A., Goesmann, A., Vorhölter, F.-J., Pühler, A. & Jahn, D. (2014)

Genome sequence of the acute urethral catheter isolate Pseudomonas aeruginosa MH38

GenomeA, 2:e00161-14


PUBMED: 23974024
Tielen, P., Wibberg, D., Blom, J., Rosin, N., Meyer, A.-K., Bunk, B., Schobert, M., Tüpker, R., Schatschneider, S., Rückert, C., Albersmeier, A., Goesmann, A., Vorhölter, F.-J., Jahn, D. & Pühler, A. (2014)

Genome sequence of the small colony variant Pseudomonas aeruginosa MH27 isolated from a chronic urethral catheter infection

GenomeA, 2:e01174-13



PUBMED: 23179618
Magnowska, Z., Hartmann, I., Jänsch, L. & Jahn, D. (2014)
Membrane proteomics of Pseudomonas aeruginosa

Methods Mol Biol., 1149: 213-224


Schomburg, D., Retter, I. & Jahn, D. (2014)
Braunschweiger Systembiologie-Zentrum BRICS - Systembiologie für Infektionsforschung und Biotechnologie

Systembiologie.de, 08:28-31


Jahn, D. (2014)
Erreger und Epidemiologie - Clostridium difficile im Visier

Thieme Praxis Report 6 (7), 1-12

PUBMED: 23974024
Ebert, M.*, Laaß, S.*, Burghartz, M., Petersen, J., Koßmehl, S., Wöhlbrand, L., Rabus, R., Wittmann, C., Tielen, P. & Jahn, D. (2013)
Transposon mutagenesis identified chromosomal and plasmid encoded genes essential for the adaptation of the marine bacterium Dinoroseobacter shibaeto anaerobic conditions.

J Bacteriol., 195:4769-4777

*contributed equally to this work


PUBMED: 23823498
Patzelt, D., Wang, H., Buchholz, I., Rohde, M., Gröbe, L., Pradella, S., Neumann, A., Schulz, S., Heyber, S., Münch, K., Münch, R., Jahn, D., Wagner-Döbler, I. & Tomasch, J. (2013)
You are what you talk: quorum sensing induces individual morphologies and cell division modes in Dinoroseobacter shibae

ISME J., 7:2274-2286


PUBMED: 23967252
Tielen, P., Rosin, N., Dohnt, K., Haddad, I., Jänsch, L., Klein J., Meyer, A.-K., Narten, M., Pommerenke, C., Scheer, M., Schobert., M., Schomburg, D. & Jahn, D. (2013)
Regulatory and metabolic networks for the adaptation of Pseudomonas aeruginosa biofilms to urinary tract-like conditions

PLOS ONE 8: e71845. doi:10.1371/journal.pone.0071845


PUBMED: 23695583
Frädrich, C., Krausze, J.,  Quade, N., Schubert, M., Heinz, D.W., Jahn, D. & Härtig, E. 
(2013)
Purification, crystallization and preliminary X-ray analysis of the effector domain of AlsR, a LysR-type transcriptional regulator of Bacillus subtilis

Acta crystallographica Section F, 69:581-584


PUBMED: 23363548
Kaufholz, A.-L., Hunter, G. A., Ferreira, G. A., Lendrihas, T., Hering, V., Layer, G., Jahn, M. & Jahn D.  (2013)
Aminolevulinic acid synthase of Rhodobacter capsulatus - high resolution kinetic investigation of the structural basis for substrate binding and catalysis

Biochem J., 451:205-216


PUBMED: 23341615
Moser, J., Lange, C., Krausze, J.,  Rebelein, J., Schubert, W.-D., Ribbe, M., Heinz, D.W. & Jahn, D.  (2013)
Structure of ADP•AlF3-stabilized protochlorophyllide oxidoreductase complex

Proc Natl Acad Sci USA, 110:2094-2098


PUBMED: 23036925
Steen, A., Ütkür, F.Ö., Borrero-de Acuña, J.M., Bunk, B., Roselius, L., Bühler, B., Jahn, D. & Schobert, M. (2013)
Construction and characterization of nitrate and nitrite respiring Pseudomonas putida KT2440 strains for anoxic biotechnical applications

J Biotechnol., 163:155-165


PUBMED: 22750448
Korneli, C., David, F., Biedendieck, R., Jahn, D. & Wittmann, C. (2013)
Getting the big beast to work--systems biotechnology of Bacillus megaterium for novel high-value proteins

J Biotechnol. 163: 87-96.


PUBMED: 23179620
Korneli, C., Biedendieck, R., David, F., Jahn, D. & Wittmann, C. (2013)
High yield production of extracellular recombinant levansucrase by Bacillus megaterium

Appl Microbiol Biotechnol., 97:3343-3353


PUBMED: 23179618
Diekmann, N., Burghartz, M., Remus, L., Kaufholz, A.-L., Nawrath, T., Rohde, M., Schulz, S., Roselius, L., Schaper, J., Mamber, O., Jahn, D. & Jahn, M. (2013)
Microbial communities related to volatile organic compound emission in automobile air conditioning units

Appl Microbiol Biotechnol., 97: 8777-8793



Kaufholz, A.-L., Layer, G., Heinz, D., Jahn M. & Jahn, D. (2013)
The Structural Basis of Porphyrias - Defects of Heme Biosynthetic Enzymes

in Handbook of Porphyrin Science, Vol. 29, Ferreira, G. C., Kadish, K. M., Smith, K. M. (Eds.), p. 1 - 42, World Scientific Pub. Co. Pte. Ltd., Singapore.


PUBMED: 23046954
Härtig, E. & Jahn, D. (2012)
Regulation of the Anaerobic Metabolism in Bacillus subtilis

Adv Microb Physiol., 61:195-216


PUBMED: 22772947
Klein, J., Leupold, S., Biegler, I., Biedendieck, R., Münch, R. & Jahn, D. (2012)
TLM-Tracker: Software for cell segmentation, tracking and lineage analysis in time-lapse microscopy movies

Bioinformatics, 28: 2276-2277

http://www.tlmtracker.tu-bs.de


PUBMED: 22178965
Frädrich, C., March, A., Fiege, K., Hartmann, A., Jahn, D. & Härtig, E. (2012)
The transcription factor AlsR binds and regulates the promoter of the alsSD operon responsible for acetoin formation in Bacillus subtilis

J Bacteriol., 194: 1100-1112


PUBMED: 22142238
Abicht, H.K., Martinez, J., Layer, G., Jahn, D. & Solioz, M. (2012)
Lactococcus lactis HemW (HemN) is a heme-binding protein with a putative role in heme trafficking

Biochem J., 442: 335-343


PUBMED: 22155866
Shevshuk, O., Roselius, L., Günther, G., Klein, J., Jahn, D., Steinert, M. & Münch, R. (2012)
InFiRe – a novel computational method for the identification of insertion sites in transposon mutagenized bacterial genomes

Bioinformatics, 28:306-310



Jahn, D., Krull, R. & Wittmann, C. (Eds.) (2012)
From gene to product – Development of biotechnological processes by integrating genetic and engineering methods. Concluding reports, collaborative research centre SFB 578.

Cuvillier Verlag, Göttingen 2012, ISBN 978-3-642-17305-9 2.


Jahn, M. & Jahn, D. (2012)
Electron transfer reactions and oxidative phosphorylation

in "Biochemical pathways: an atlas of biochemistry and molecular biology" Michal, G., Schomburg, D. (Eds.), John Wiley & Sons, p 183-187


Jahn, M. & Jahn, D. (2012)
Tetrapyrroles

in "Biochemical pathways: an atlas of biochemistry and molecular biology" Michal, G., Schomburg, D. (Eds.), John Wiley & Sons, p 82-92


Jahn, M. & Jahn, D. (2012)
Protein synthesis in bacteria

in "Biochemical pathways: an atlas of biochemistry and molecular biology" Michal, G., Schomburg, D. (Eds.), John Wiley & Sons, p 210-218.


Tielen, P., Schobert, M., Härtig, E. & Jahn, D. (2012)
Anaerobic regulatory networks in bacteria

in "Bacterial regulatory networks", Filloux, A. A. M. (Ed.), Horizon Academic Press, Norwich, UK, 273 - 305


Bröcker, M., Jahn, D. & Moser, J. (2012)
Key Enzymes of Chlorophyll Biosynthesis

in "Handbook of Porphyrin Science", 20, 1-43



PUBMED: 21935588
Borgmeier, C., Biedendieck, R., Hoffmann, K., Jahn, D. & Meinhardt, F. (2011)
Transcriptome profiling of degU expression reveals unexpected regulatory patterns in Bacillus megaterium and discloses new targets for optimizing expression 

Appl Microbiol Biotechnol., 92: 583-596


PUBMED: 21705586
Eppinger, M., Bunk, B., Johns, M.A., Edirisinghe, J.N., Kutumbaka, K.K., Koenig, S.S.K., Creasy, H.H., Rosovitz, M.J., Riley, D.R., Daugherty, S., Martin, M., Elbourne, L.D.H., Paulsen, I., Biedendieck, R., Braun, C., Grayburn, Dhingra, S., Lukyanchuk, V., Ball, B., ul-Qamar, R., Seibel, J., Bremer, E., Jahn, D., Ravel, J. & Vary, P.S. (2011)
Genome sequences of the biotechnologically important B. megaterium strains QM B1551 and DSM319 

J Bacteriol. 193: 4199-4213
 


Piekarski, T., Jahn, D. & Tielen, P. (2011)
Marine Mikrobiologie: Etablierung genetischer Werkzeuge für Bakterien der Roseobacter-Gruppe.

BIOspektrum 04/11 


PUBMED: 21454585
Strube, C.P., Homann, A., Gamer, M., Jahn, D., Seibel, J. & Heinz, D.W. (2011)
Polysaccharide synthesis of the levansucrase SACB from Bacillus megaterium is controlled by distinct surface motifs.

J Biol Chem. 286: 17593-17600


PUBMED: 21392131
Hebecker, S., Arendt, W., Heinemann, I.U., Tiefenau, J.H.J., Nimtz, M., Rohde, M., Söll, D., & Moser, J.. (2011)
Alanyl-Phosphatidylglycerol Synthase: Mechanism of Substrate Recognition during tRNA-dependent Lipid Modification in Pseudomonas aeruginosa.

Mol Microbiol.80: 935-950


PUBMED:  21943898
Biedendieck, R., Borgmeier, C., Bunk, B., Stammen, S., Scherling, C., Meinhardt, F., Wittmann, C. & Jahn, D. (2011)
Systems biology of recombinant protein production using Bacillus megaterium. 

Methods Enzymol., 500: 165-195 


PUBMED: 21219871
De Armas-Ricard, M., Levicán, G., Katz, A., Moser, J., Jahn, D. & Orellana, O. (2011)
Cellular levels of heme affect the activity of glutamyl-tRNA reductase.

Biochem. Biophys. Res. Com., 405: 134-139


PUBMED: 21310745 
Bartsch , A., Bunk , B., Haddad , I., Klein , J., Münch , R., Johl , T., Kärst , U., Jänsch , L., Jahn, D. & Retter, I. (2011)  
GeneReporter – Sequence based document retrieval andannotation

Bioinformatics, 27: 1034-1035


PUBMED: 21110836
Garbe, J., Wesche, A., Bunk, B., Kazmierczak, M., Selezska, K., Rohde, C., Sikorski, J.,  Rohde, M., Jahn, D. & Schobert, M. (2011)  
Characterization of JG024, a Pseudomonas aeruginosa PB1- like broad host range phage under simulated infection conditions.

BMC Microbiol., 10:301


Münch, R., Klein, J. & Jahn, D. (2011)
Bookchapter: Prediction and Analysis of Gene Regulatory Networks in Prokaryotic Genomes. Bioinformatics - Experimental Biology Systems ISBN 978-953-307-280-7. InTech - Open Access Publisher



    PUBMED: 21068385
    Gruner, I, Frädrich, C, Böttger H.L., Trautwein, A.X., Jahn, D. & Härtig, E. (2010)
    Aspartate 141 it the fourth ligand of the oxygen sensing [4Fe-4S]2+ cluster of Bacillus subtilis transcriptional regulator Fnr

    J. Biol. Chem., 286:2017-2021


    PUBMED: 20951638 
    Schobert, M. & Jahn, D. (2010)
    Anaerobic physiology of Pseudomonas aeruginosa in the cystic fibrosis lung.

    Int. J. Med. Microbiol., 300:549-456


    PUBMED: 21193347 
    Tielen, P., Narten, M., Rosin, N., Biegler, I., Haddad, I., Hogardt, M., Neubauer, R., Schobert, M., Wiehlmann, L. & Jahn, D. (2010)
    Genotypic and phenotypic characterization of Pseudomonas aeruginosa isolates from urinary tract infections.

     Int. J. Med. Microbiol., 301: 282-292


    PUBMED: 21197080
    Storbeck, S., Rolfes, S., Raux-Deery, E., Warren, M.J., Jahn, D. & Layer, G. (2010)
    A novel pathway for the biosynthesis of heme in Archaea: Genome-based bioinformatic predictions and experimental evidence.

    Archaea 2010, ID 175050 


    PUBMED: 20670661
    David, F., Westphal, R., Bunk, B., Jahn, D. & Franco-Lara, E. (2010)
    Optimization of antibody fragment production in Bacillus megaterium: the role of metal ions on protein secretion.

    J Biotechnol. 150:115-124. 


    PUBMED: 20823549
    Haffke, M., Menzel, A., Carius, Y., Jahn, D. & Heinz, D.W. (2010)
    Structures of the nucleotide-binding domain of the human ABCB6 transporter and its complexes with nucleotides.

    Acta Cryst. 66:979-987 


    PUBMED: 20546309 
    Rosenau, F., Isenhardt, S., Gdynia, A., Tielker, D., Schmidt, E., Tielen, P., Schobert, M., Jahn, D., Wilhelm, S. & Jaeger, K.E. (2010)
    Lipase LipC affects motility, biofilm formation and rhamnolipid production in Pseudomonas aeruginosa.

    FEMS Microbiol Lett.  309:25-34.


    PUBMED: 20596705 
    Stammen, S., Schuller, F., Dietrich, S., Gamer, M., Biedendieck, R. & Jahn, D. (2010)
    Application of Escherichia coli phage K1E DNA-dependent RNA polymerase for in vitro RNA synthesis and in vivo protein production in Bacillus megaterium.

    Appl. Microbiol. Biotechnol. 88: 529-539


    PUBMED: 20553007 
    Silva, P., Schulz, C., Jahn, M., Jahn, D. & Ramos, M. (2010)
    A Tale of two acids: When arginine is a more appropriate acid than H3O+.

    J Phys Chem 114: 8994-9001


    PUBMED: 20558746
    Bröcker, M., Schomburg, S., Heinz, D.W., Jahn, D., Schubert, W.D. & Moser, J. (2010)
    Crystal structure of the nitrogenase-like dark operative protochlorophyllide oxidoreductase catalytic complex (ChlN/ChlB)2.

    J. Biol Chem 285:27336-27345  


    PUBMED: 20484676
    Möbius, K., Arias-Cartin, R., Breckau, D., Haennig, A.-L.,  Riedmann, K., Biedendieck, R., Schroeder, S., Becher, D., Magalon, A.,  Moser, J.,  Jahn, M. & Jahn, D. (2010)
    Heme biosynthesis is coupled to electron transport chains for energy generation 

    Proc. Natl. Acad. Sci. USA 107:10436-10441. 


    PUBMED: 20435764
    Stammen, S., Müller, B.K., Korneli, C., Biedendieck, R., Gamer, M., Franco-Lara, E. & Jahn, D. (2010)
    High yield intra- and extracellular protein production using Bacillus megaterium

    Appl. Environ. Microbiol. 76: 4037-4046


    PUBMED: 20506125
    Layer, G., Reichelt, J., Jahn, D. & Heinz, D.W. (2010)
    Structure and function of enzymes in heme biosynthesis

    Protein Science 19, 1137-1161


    PUBMED: 20553552
    Trunk, K., Benkert, B., Quaeck, N., Muench, R., Scheer, M., Garbe, J., Jaensch, J., Trost, M., Wehland, J., Buer, J., Jahn, M., Schobert, M. & Jahn, D. (2010)
    Anaerobic adaptation in Pseudomonas aeruginosa: Definition of the Anr and Dnr Regulons.

    Environ. Microbiol. 12, 1719-1733


    PUBMED: 20075073 
    Bröcker, M., Wätzlich, D., Saggu, M., Lendzian, F., Moser, J. & Jahn, D. (2010)
    Biosynthesis of (bacterio)chlorophylls: ATP-dependent transient subunit interaction and electron transfer of dark operative protochlorophyllide oxidoreductase.

    J. Biol Chem 285: 8268-8277


    PUBMED: 21326933 
    B
    unk, B., Schulz, A., Stammen, S., Münch, R., Warren, M. J., Rohde, M., Jahn, D. & Biedendieck, R. (2010)
    A short story about a big magic bug.

    Bioengineered Bugs 1: 1-7


    PUBMED: 21255303 
    Biedendieck, R., Malten, M., Barg, H., Bunk, B., Martens, J.-H., Deery, E., Leech, H., Warren, M. J. & Jahn, D. (2010)
    Metabolic engineering of cobalamin (vitamin B12) production in Bacillus megaterium.

    Microbial Biotechnology 3: 24–37



    Jahn, D., & Jahn, M. (2010)
    Warum sind Bakterien unsere Freunde? In: Kinder-Uni Braunschweig-Wolfsburg (Sandhagen, P., Ed.), Westermann
    Verlag Braunschweig, 13-30


    PUBMED: 20140656
    Biedendieck, R., Bunk, B., Fürch, T., Franco-Lara, E., Jahn, M. & Jahn, D. (2010)
    Systems Biology of Recombinant Protein Production in Bacillus megaterium in "Advances in Biochemical Engineering / Biotechnology"

    (Scheper, T., Ed.); Biosystems Engineering (Wittmann, C., Ed.)
    Springer, Berlin, Heidelberg 120: 133-161  


    Bunk, B., Biedendieck, R., Jahn, D. & Vary, P. S. (2010)
    Bacillus megaterium and other Bacilli, Industrial Applications
    In Flickinger M. C. (Ed.) Encyclopedia of Industrial Biotechnology: Bioprocess, Bioseparation, and Cell Technology.

    Volume 1 pp 429-443. John Wiley & Sons. Inc., Hoboken, NJ.


    Layer, G., Jahn, D., Deery, E., Lawrence, A.D. & Warren, M. (2010)
    Biosynthesis of heme and vitamin B12 in "Comprehensive natural products II Chemistry and Biology"
    (Mander, L., Lui, H.-W.)

    Elsevier: Oxford; 7:445–499


    PUBMED: 20021642
    Piekarski, T., Buchholz, I., Drepper, T., Schobert, M., Wagner-Doebler, I., Tielen, P. & Jahn, D. (2009)
    Genetic tools for the investigation of Roseobacter clade bacteria. 

    BMC Microbiology, 9: 265


    PUBMED: 19822707
    Heinemann, I.U., Schulz, C., Schubert, W.D., Heinz, D., Wang, Y.G., Kobashi, Y., Awa, Y., Wachi, M., Jahn, D. & Jahn, M. (2009)
    Structure of the heme biosynthetic Pseudomonas aeruginosa porphobilinogen synthase in complex with the antibiotic alaremycin.

    Antimicrobial Agents and Chemotherapy 54: 267-572


    PUBMED: 19741735
    Wagner-Döbler, I., Ballhausen, B., Baumgart, M., Brinkhoff, T., Buchholz, I., Bunk, B., Cypionka, H., Daniel, R., Drepper, T., Gerdts, G., Hahnke, S., Han, C., Jahn, D., Kalhoefer, D., Kiss, H., Klenk, H.-P., Kyrpides, N., Liebl, W., Liesegang, H., Meincke, L., Pati, A., Petersen, J., Piekarski, T., Pommerenke, C., Pradella, S., Pukall, R., Rabus, R., Stackebrandt, E., Thole, S., Thompson, L., Tielen, P., Tomasch, J., von Jan, M., Wanphrut, N., Wichels, A., Zech, H. & Simon, M. (2009)
    The complete genome sequence of the algal symbiont Dinoroseobacter shibae; a hitchhiker`s guide to life in the sea.

    ISME Journal 4:61-77 


    Beine, R., Valente, A.R., Biedendieck, R., Jahn, D. & Seibel, J. (2009)
    Directed optimization of biocatalytic transglycosylation processes by the integration of genetic algorithms and fermentative approaches into a kinetic model.

    Process Biochemistry 44: 1103–1114 


    PUBMED: 19336405 
    Wätzlich, D., Bröcker, M., Uliczka, F., Ribbe, M., Virus, S.; Jahn, D. & Moser, J. (2009)
    Chimeric nitrogenase-like enzymes of (bacterio)chlorophyll biosynthesis.

    J. Biol Chem 284:15530-15540


    PUBMED: 20109147
    Haddad, I., Hiller, K., Frimmersdorf, E., Benkert, B., Schomburg, D. & Jahn, D. (2009)
    An Emergent Self-organizing Map Based Analysis Pipeline for Comparative Metabolome Studies.

    In Silico Biology 9:149-162 


    PUBMED: 19308404
    Gamer, M., Froede, D., Biedendieck, R., Stammen, S. & Jahn, D. (2009)
    A T7 RNA polymerase-dependent gene expression system for Bacillus megaterium.

    Appl Microbiol Biotechnol. 82:1195-1203


    PUBMED: 19087229
    Klein, S., Lorenzo, C., Hoffmann, S., Walther, J. M., Storbeck, S., Piekarski, T., Tindall, B. J., Wray, V., Nimtz, M. & Moser, J. (2009)
    Adaptation of Pseudomonas aeruginosa to various conditions includes tRNA-dependent formation of alanyl-phosphatidylglycerol.

    Mol Microbiol 71:551-565


    PUBMED: 18974177
    Grote, A., Klein, J., Retter, I., Haddad, I., Behling, S., Bunk, B., Biegler, I., Yarmolinetz, S., Jahn, D. & Münch, R. (2009)
    PRODORIC (release 2009): a database and tool platform for the analysis of gene regulation in prokaryotes.

    Nucleic Acids Res. Database issue D61-5


    PUBMED: 19025572
    Walther, J., Bröcker, M., Wätzlich, D., Nimtz, M., Rohde, M., Jahn, D. & Moser, J. (2009)

    Protochlorophyllide: A new photosensitizer for the photodynamic inactivation of Gram-positive and Gram-negative bacteria.

    FEMS Microbiol. Lett. 296:156-163


    PUBMED: 18854354
    Klein, J., Münch, R., Biegler, I., Haddad, I., Retter, I. & Jahn, D. (2009)
    Strepto-DB, a database for comparative genomics of group A (GAS) and B (GBS) streptococci, implemented with the novel database platform ‘Open Genome Resource’ (OGeR)

    Nucleic Acids Res. Database issue D494-8



    Jahn, D. & Heinz, D.W. (2009)
    Biosynthesis of 5-aminolevulinic acid
    in Tetrapyrroles-Birth, life and death (Warren, M.J., Smith, A. G., Eds.)

    Landes Bioscience, Austin, Texas, USA


    Tielen, P., Hogardt, M., Schobert, M., Heesemann, J., & Jahn, D. (2009)
    Systembiologie der Harnwegs- und Wundinfektion durch Pseudomonas aeruginosa

    GENOMEXPRESS 3.09, 17-19


    Schilling, M., Hempel, D.C., & Jahn, D. (2009)
    Vom Gen zum Produkt - aber mit System

    Spektrum der Wissenschaft 10/09, 34-41


    Jahn, D., & Schomburg, D. (2009)
    Quo vadis Systembiologie

    BIOspektrum 15, 07.09, 810-811


    Jahn, M. & Jahn, D. (2009)

    Regulation und Systembiologie in "Taschenlehrbuch Biologie - Genetik"

    (Munk, K., Ed.)
    Thieme Verlag


    Jahn, M. & Jahn, D. (2009)

    Milk fat rancidity in “Handbook of Hydrocarbon and Lipid Microbiology”
    (Timmis, KN, Ed.)
    Springer Verlag, Berlin, Germany


    Jahn, M. & Jahn, D. (2008)

    Anpassungsfähigkeit von Mikroorganismen in “Taschenlehrbuch Biologie - Mikrobiologie” (Munk, K., Rd.)

    Thieme Verlag


    Dersch, P. & Jahn, D. (2008)

    Mikrobielle Genetik in “Taschenlehrbuch Biologie - Mikrobiologie”
    (Munk, K., Rd.)

    Thieme Verlag


    PUBMED: 19047738
    Masoumi, A., Heinemann, I. U., Rohde, M., Koch, M., Jahn, M. & Jahn D. (2008)
    Complex formation between Protoporphyrinogen IX Oxidase and Ferrochelatase during Heme Biosynthesis in Thermosynechococcus elongatus.

    Microbiology. 154:3707-3714


    PUBMED: 18693243
    Bröcker, M., Wätzlich, D., Uliczka, F., Virus, S., Saggu, M., Lendzian, F., Scheer, H., Rüdiger, W., Moser, J. & Jahn, D. (2008)
    Substrate Recognition of Nitrogenase-like Dark Operative Protochlorophyllide Oxidoreductase from Prochlorococcus marinus.

    J. Biol. Chem. 283:29873-29881


    PUBMED: 18832311
    Benkert, B., Quäck, N., Schreiber, K., Jaensch, L., Jahn, D. & Schobert, M. (2008)
    Nitrate responsive NarX-NarL represses arginine mediated induction of the Pseudomonas aeruginosa arginine fermentation arcDABC operon.

    Microbiology. 154:3053-3060


    PUBMED: 18440972
    Klein, J., Leupold, S., Münch, R., Pommerenke, C., Johl, T., Kärst, U., Jänsch, L., Jahn, D. and Retter, I. (2008)
    ProdoNet: identification and visualization of prokaryotic gene regulatory and metabolic networks.

    Nucleic Acids Res. 36:W460-464


    PUBMED: 18928204
    Pommerenke, C., Gabriel, I., Bunk, B., Münch, R., Haddad, I., Tielen, P., Wagner-Döbler I. & Jahn D. (2008)
    ROSY - a flexible and universal database and bioinformatics tool platform for Roseobacter related species.

    In Silico Biol. 8:177-186


    PUBMED: 18314007
    Heinemann, I. U., Jahn, M. & Jahn, D. (2008)
    The biochemistry of heme biosynthesis.

    Arch Biochem Biophys. 474:238-251. Review


    PUBMED: 18252716
    Bröcker, M.J., Virus, S., Ganskow, S., Heathcote, P., Heinz, D.W., Schubert, W-D., Jahn, D. & Moser, J. (2008)
    ATP-Driven Reduction by Dark-Operative Protochlorophyllide Oxidoreductase from Chlorobium tepidum Mechanistically Resembles Nitrogenase Catalysis.

    J. Biol. Chem. 283:10559-10567


    PUBMED: 18042043
    Tan, F.-C., Cheng,Q., Saha, K., Heinemann, I. U., Jahn, M., Jahn D. & Smith, A.G. (2008)
    Identification and characterization of the Arabidopsis gene encoding the tetrapyrrole biosynthesis enzyme uroporphyrinogen III synthase.

    Biochem. J. 410:291-299



    PUBMED: 17826861
    Fürch, T., Wittmann, C., Wang, W., Franco-Lara, E., Jahn, D. & Deckwer, W. D. (2007)
    Effect of different carbon sources on central metabolic fluxes and the recombinant production of a hydrolase from Thermobifida fusca in Bacillus megaterium.

    J. Biotechnol. 132:385-394


    PUBMED: 17929881
    Huot, J., Balg, C., Jahn, D., Moser, J., Émond, A., Blais, S, Chênevert, R. & Lapointe, J. (2007)
    Mechanism of a GatCAB amidotransferase: aspartyl-tRNA synthetase increases its affinity for Asp-tRNAAsn, and novel aa-tRNA analogs are competitive inhibitors.

    Biochemistry 46:13190-13198


    PUBMED: 17697121
    Lüer, C., Schauer, S., Virus, S., Schubert, W.D., Heinz, D.W., Moser, J.& Jahn, D. (2007)
    Glutamate Recognition and Hydride Transfer by Escherichia coli Glutamyl-tRNA Reductase.

    FEBS Journal 274:4609-4614


    PUBMED: 17692983
    Biedendieck, R., Gamer, M., Jaensch, L., Meyer, S., Rohde, M., Deckwer, W.-D. & Jahn, D. (2007)
    A sucrose-inducible promoter system for the intra- and extracellular protein production in Bacillus megaterium.

    J Biotechnol. 132:426-430


    PUBMED: 17608626
    Homann, A., Biedendieck, R., Goetze, S., Jahn, D. & Seibel, J. (2007)
    Insights into polymer versus oligosaccharide synthesis: Mutagenesis and mechanistic studies of a novel levansucrase from Bacillus megaterium.

    Biochem J. 407:189-198


    PUBMED: 17619232
    Bäumchen, C., Roth, A. H. F. J., Biedendieck, R., Malten, M., Follmann, M., Sahm, H., Bringer-Meyer, S. & Jahn, D. (2007)
    D-Mannitol production by resting state whole cell biotransformation of D-fructose by heterologous mannitol and formate dehydrogenase genes expression in Bacillus megaterium.

    Biotechnol J. 2:1408-1416


    PUBMED: 17657486
    Vary, P. S., Biedendieck, R., Fuerch, T., Meinhardt, F., Rohde, M., Deckwer, W.-D. & Jahn, D. (2007)
    Bacillus megaterium – from simple soil bacterium to industrial protein production host.

    Appl Microbiol Biotechnol. 76:957-967. Review


    PUBMED: Link
    Klawonn, F., Choi, C., Benkert, B., Thielen, B., Münch, R., Schobert, M., Schomburg, D. & Jahn, D. (2007)
    A Likelihood Ratio Test for Differential Metabolic Profiles in Multiple Intensity Measurements.

    KES2007 Invited Sessions k07is-136


    PUBMED: 17400734
    Schreiber, K., Krieger, R., Benkert, B., Eschbach, M., Arai, H., Schobert, M. & Jahn, D. (2007)
    The anaerobic regulatory network required for Pseudomonas aeruginosa nitrate respiration.

    J Bacteriol. 189:4310-4314


    PUBMED: Link
    Choi, C., Münch, R., Bunk, B., Barthelmes, J., Ebeling, C., Schomburg, D., Schobert, M. & Jahn, D. (2007)
    Combination of a data warehouse concept with web services for the establishment of the Pseudomonas systems biology database SYSTOMONAS.

    Journal of Integrative Bioinformatics 4:48


    PUBMED: 17224052
    Jordan, E., Hust, M., Roth, A., Biedendieck, R., Schirrmann, T., Jahn, D. & Duebel, S. (2007)
    Production of recombinant antibody fragments in Bacillus megaterium.

    Microb Cell Fact. 6:2


    PUBMED: 17134376
    Heinemann, I.U., Diekmann, N., Masoumi, A., Koch, M., Messerschmidt, A., Jahn, M. & Jahn, D. (2007)
    Functional definition of the tobacco protoporphyrinogen IX oxidase substrate binding site.

    Biochem J. 402:575-580


    PUBMED: 17245578
    Biedendieck, R., Beine, R., Gamer, M., Jordan, E., Buchholz, K., Seibel, J., Dijkhuizen, L., Malten, M. & Jahn, D. (2007)
    Export, purification and activities of affinity tagged Lactobacillus reuteri levansucrase produced by Bacillus megaterium.

    Appl Microbiol Biotechnol. 74:1062-1073


    PUBMED: 16948171
    Yang, Y., Malten, M., Grote, A., Jahn, D. & Deckwer, W.D. (2007)
    Codon optimized Thermobifida fusca hydrolase secreted by Bacillus megaterium.

    Biotechnol Bioeng. 96:780-794


    PUBMED: 16964623
    Biedendieck, R., Yang, Y., Deckwer, W.-D., Malten, M. & Jahn, D. (2007)
    Plasmid system for the intracellular production and purification of affinity-tagged proteins in Bacillus megaterium.

    Biotechnol Bioeng. 96, 525-537


    PUBMED: 17202169
    Choi, C., Muench, R., Leupold, S., Klein, J., Siegel, I., Thielen, B., Benkert, B., Kucklick, M., Schobert, M., Barthelmes, J., Ebeling, C., Haddad, I., Scheer, M., Grote, A., Hiller, K., Bunk, B., Schreiber, K., Retter, I., Schomburg, D. & Jahn, D. (2007)
    SYSTOMONAS - an integrated database for systems biology analysis of Pseudomonas.

    Nucleic Acid Res. 35(Database Issue), D533-D537


    Jahn, D., Moser, J., Schubert, W. & Heinz, D (2006)
    Transfer RNA-dependent aminolevulinic acid formation of glutamyl-tRNA synthetase, reductase and glutamate-1-semialdehyde-2,1-aminomutase, Vol. 25, B. Grimm, R. Porra, W. Rüdiger, H. Scheer (eds.) Chlorophylls and Bacteriochlorophylls: Biochemistry, Biophysics, Functions and Applications, pp. 445-459. Springer, Dordrecht, The Netherlands


    PUBMED: 17132166
    Yang, Y., Biedendieck, R., Wang, W., Gamer, M., Malten, M., Jahn, D. & Deckwer, W.-D. (2006)
    High yield recombinant penicillin G amidase production and export into the growth medium using Bacillus megaterium.

    Microb Cell Fact. 5:36


    PUBMED: 17046977
    Bunk, B., Kucklick, M., Jonas, R., Munch, R., Schobert, M., Jahn, D. & Hiller, K. (2006)
    MetaQuant: a tool for the automatic quantification of GC/MS based metabolome data.

    Bioinformatics. 22, 2962-2965


    PUBMED: 17028275
    Buchenau, B., Kahnt, J., Heinemann, I.U., Jahn, D. & Thauer, R.K. (2006)
    Heme biosynthesis in Methanosarcina barkeri via a pathway involving two methylation reactions.

    J Bacteriol. 188, 8666-8668


    PUBMED: 16885274
    Haertig, E., Hartmann, A., Schatzle, M., Albertini, A.M. & Jahn, D. (2006)
    The Bacillus subtilis nrdEF genes, encoding a class Ib ribonucleotide reductase, are essential for aerobic and anaerobic growth.

    Appl Environ Microbiol. 72, 5260-5265


    PUBMED: 16876193
    Schulze, J.O., Masoumi, A., Nickel, D., Jahn, M., Jahn, D., Schubert, W.D. & Heinz D.W. (2006)
    Crystal Structure of a Non-discriminating Glutamyl-tRNA Synthetase.

    J Mol Biol. 361, 888-897


    PUBMED: 16870933
    Hiller, K., Grote, A., Maneck, M., Muench, R. & Jahn, D. (2006)
    JVirGel 2.0: computational prediction of proteomes separated via two dimensional gel electrophoresis under consideration of membrane and secreted proteins.

    Bioinformatics 22, 2441-2443


    PUBMED: 16845060
    Scheer, M., Klawonn, F., Muench, R., Grote, A., Hiller, K., Choi, C., Koch, I., Schobert, M., Haertig, E., Klages, U. & Jahn, D. (2006)
    JProGO: A novel tool for the functional interpretation of prokaryotic microarray data using Gene Ontology information.

    Nucleic Acids Res. 34, 510-515


    PUBMED: 16796679
    Reents, H., Gruner, I., Harmening, U., Böttger, L.H., Layer, G., Heathcote, P., Trautwein, A.X., Jahn,D. & Haertig, E. (2006)
    Bacillus subtilis Fnr senses oxygen via a [4Fe-4S]-cluster coordinated by three cysteine residures without change in the oligomeric state.

    Mol. Microbiol. 60, 1432-1445


    PUBMED: 16606627
    Layer, G., Pierik, A.J., Trost, M., Rigby, S.E., Leech, H.K., Grage, K., Breckau, D., Astner, I., Jaensch, L., Heathcote, P., Warren, M.J., Heinz, D.W. & Jahn,D. (2006)
    The substrate radical of Escherichia coli oxygen-independent coproporphyrinogen III oxidase HemN.

    J. Biol. Chem. 281. 15272-15734


    PUBMED: 16567015
    Sun, J., Wang, W., Hundertmark, C., Zeng, A.P., Jahn, D. & Deckwer, W.D. (2006)
    A protein database constructed from low-coverage genomic sequence of Bacillus megaterium and its use for accelerated proteomic analysis.

    J. Biotechnol. 124, 486-495


    PUBMED: 16564539
    Schulze, J.O., Schubert, W.D., Moser, J., Jahn, D. & Heinz, D.W. (2006)
    Evolutionary Relationship between Initial Enzymes of Tetrapyrrole Biosynthesis.

    J. Mol. Biol. 358, 1212-1220


    PUBMED: 16461726
    Malten, M., Biedendieck, R., Gamer, M., Drews, A.C., Stammen, S., Buchholz, K., Dijkhuizen, L. & Jahn D (2006)
    A Bacillus megaterium plasmid system for the production, export, and one-step purification of affinity-tagged heterologous levansucrase from growth medium.

    Appl. Environ. Microbiol. 72, 1677-1679


    Deckwer, W.-D., Hempel, D.C., Zeng, A.-P. & Jahn D (2006)
    Systembiotechnologische Ansätze zur Prozessentwicklung.

    Chemie Ingenieur Technik 78, 193-208


    Hollmann, R., Malten, M., Biedendieck, R., Yang, Y., Wang, W., Jahn, D. & Deckwer, W.-D. (2006)

    Bacillus megaterium als Produktionssystem für rekombinante Proteine.
    Chemie Ingenieur Technik 78, 289-294


    PUBMED: 16428414
    Reents, H., Muench, R., Dammeyer, T., Jahn, D. & Haertig, E. (2006)
    The Fnr Regulon of Bacillus subtilis.

    J. Bacteriol. 188, 1103-1112


    PUBMED: 16109747
    Muench, R., Hiller, K., Grote, A., Scheer, M., Klein, J., Schobert, M. & Jahn, D. (2005)
    Virtual Footprint and PRODORIC: an integrative framework for regulon prediction in prokaryotes.

    Bioinformatics 21, 4187-4189


    PUBMED: 16218869
    Layer, G., Kervio, E., Morlock, G., Heinz, D.W., Jahn, D., Retey, J. & Schubert, W.D. (2005)
    Structural and functional comparison of HemN to other radical SAM enzymes.

    Biol Chem. 386, 971-980. Review


    PUBMED: 16121195
    Astner, I., Schulze, J.O., van den Heuvel, J., Jahn, D., Schubert, W.D. & Heinz DW. (2005)
    Crystal structure of 5-aminolevulinate synthase, the first enzyme of heme biosynthesis, and its link to XLSA in humans.

    EMBO J. 24, 3166-3177


    PUBMED: 15967800
    Layer, G., Grage, K., Teschner, T., Schunemann, V., Breckau, D., Masoumi, A., Jahn, M., Heathcote, P., Trautwein, A.X. & Jahn, D. (2005)
    Radical S-Adenosylmethionine Enzyme Coproporphyrinogen III Oxidase HemN: FUNCTIONAL FEATURES OF THE [4Fe-4S] CLUSTER AND THE TWO BOUND S-ADENOSYL-L-METHIONINES.

    J. Biol. Chem. 280, 29038-29046


    PUBMED: 15927046
    Wang, W., Hollmann, R., Furch, T., Nimtz, M., Malten, M., Jahn, D. & Deckwer W.D. (2005)
    Proteome analysis of a recombinant Bacillus megaterium strain during heterologous production of a glucosyltransferase.

    Proteome Sci. 3, 4


    PUBMED: 15980527
    Grote, A., Hiller, K., Scheer, M., Muench, R., Noertemann, B., Hempel, D.C. & Jahn D. (2005)
    JCat: a novel tool to adapt codon usage of a target gene to its potential expression host.

    Nucleic Acids Res. 33, 526-531


    PUBMED: 15757895
    Lüer, C., Schauer, S., Moebius, K., Schulze, J., Schubert, W.-D., Heinz, D.W., Jahn, D. & Moser J.(2005)
    Complex formation between glutamyl-tRNA reductase and glutamate-1-semialdehyde-2,1-aminomutase in Escherichia coli during the initial reaction of porphyrin biosynthesis.

    J. Biol. Chem. 280, 18568-18572


    PUBMED: 16003778
    Malten, M., Nahrstedt, H., Meinhardt, F. & Jahn, D. (2005)
    Coexpression of the type I signal peptidase gene sipM increases recombinant protein production and export in Bacillus megaterium MS941.

    Biotechnol. Bioeng. 91, 616-621


    PUBMED: 15790858
    Sauerwald, A., Zhu, W., Major, T.A., Herve, R., Palioura, S., Jahn, D., Whitman, W., Yates, J.R. 3rd., Ibba, M. & Soell, D. (2005)
    RNA-dependent cysteine biosynthesis in archaea.

    Science 207, 1969-1972


    PUBMED: 15690044
    Randau, L., Münch, R., Hohn, M., Jahn, D. & Soell, D. (2005)
    Nanoarchaeum equitans creates functional tRNA from separate genes encoding their 5'- and 3'-halves.

    Nature 433, 537-541


    PUBMED: 15644204
    Frere, F., Reents, H., Schubert, W.D., Heinz, D.W., and Jahn, D.(2005)
    Tracking the evolution of porphobilinogen synthase metal dependence in vitro.

    J. Mol. Biol. 345, 1059-1070


    PUBMED: 15593264
    Malten, M., Hollmann, R., Deckwer, W.-D. & Jahn, D. (2005)
    Production and secretion of recombinant Leuconostoc mesenteroides dextransucrase DsrS in Bacillus megaterium.

    Biotechnol. Bioeng. 89, 206-218


    PUBMED: 15450488
    Layer, G., Heinz, D.W., Jahn, D., Schubert, W.D. (2004)
    Structure and function of radical SAM enzymes.

    Curr. Opin. Chem. Biol. 8, 468-476. Review


    PUBMED: 15375128
    Haertig, E., Geng, H., Hartmann, A., Hubacek, A., Münch, R., Ye, R. W., Jahn, D. & Nakano M. M. (2004)
    Bacillus subtilis ResD Induces Expression of the Potential Regulatory Genes yclJK upon Oxygen Limitation.

    J. Bacteriol. 186, 6477-6484


    PUBMED: 15194701
    Randau, L., Schauer, S., Ambrogelly, A., Salazar, J. C., Moser, J., Sekine, S., Yokoyama, S., Soell, D. & Jahn, D. (2004)
    tRNA recognition by glutamyl-tRNA reductase.

    J. Biol. Chem. 279, 34931-34937


    PUBMED: 15231792
    Eschbach, M., Schreiber, K., Trunk, K., Buer, J., Jahn, D. & Schobert, M. (2004)
    Long-term anaerobic survival of the opportunistic pathogen Pseudomonas aeruginosa via pyruvate fermentation.

    J. Bacteriol. 186, 4596-4604


    PUBMED: 15215414
    Hiller, K., Grote, A., Scheer, M., Muench, R. & Jahn, D. (2004)
    PrediSi: prediction of signal peptides and their cleavage positions.

    Nucleic Acids Res. 32, 375-379


    Moser, J., Frere, F., Heinz, D. W., Jahn, D., and Schubert, W. (2003)
    Glutamat auf Abwegen: Die tRNA-abhängige Tetrapyrrol-Biosynthese.

    Biospektrum 2, 133-137


    PUBMED: 14550647
    Schauer, S., Lüer, C. & Moser, J. (2003)
    Large Scale Production of Escherichia coli Glutamyl-tRNA Reductase.

    Protein Expr. Purif. 31, 271-275


    PUBMED: 14663086
    Baysse, C., Matthijs, S., Schobert, M., Layer, G., Jahn, D. & Cornelis, P. (2003)
    Co-ordination of iron acquisition, iron porphyrin chelation and iron-protoporphyrin export via the cytochrome c biogenesis protein CcmC in Pseudomonas fluorescens.

    Microbiology 149, 3543-3552


    PUBMED: 14633981
    Layer, G., Moser, J., Heinz, D. W., Jahn, D. & Schubert, W. D. (2003)
    Crystal structure of coproporphyrinogen III oxidase reveals cofactor geometry of Radical SAM enzymes.

    EMBO J. 22, 6214-6224


    PUBMED: 13680202
    Frankenberg, N., Moser, J. & Jahn, D. (2003)
    Bacterial heme biosynthesis and its biotechnological application.

    Appl. Microbiol. Biotechnol. 63, 115-127. Review


    PUBMED:12975365
    Breckau, D., Mahlitz, E., Sauerwald, A., Layer, G. & Jahn, D. (2003)
    Oxygen-dependent coproporphyrinogen III oxidase (HemF) from Escherichia coli is stimulated by manganese.

    J. Biol. Chem. 278, 46625-46631


    PUBMED:12917443
    Leech, H. K., Raux, E., McLean, K. J., Munro, A. W., Robinson, N. J., Borrelly, G. P., Malten, M., Jahn, D., Rigby, S. E., Heathcote, P. & Warren, M. J. (2003)
    Characterization of the cobaltochelatase CbiXL: evidence for a 4Fe-4S center housed within an MXCXXC motif.

    J. Biol. Chem. 278, 41900-41907


    PUBMED: 12824438
    Hiller, K., Schobert, M., Hundertmark, C., Jahn, D. Muench, R. (2003)
    JVirGel: Calculation of virtual two-dimensional protein gels.

    Nucleic Acids Res. 31, 3862-3865


    PUBMED: 12829291
    Eschbach, M., Mobitz, H., Rompf, A. & Jahn, D. (2003)
    Members of the genus Arthrobacter grow anaerobically using nitrate ammonification and fermentative processes: anaerobic adaptation of aerobic bacteria abundant in soil.
    FEMS Microbiol. Lett. 223, 227-230.


    PUBMED: 12408752
    Raux, E., Leech, H. K., Beck, R., Schubert, H. L., Santander, P. J., Roessner, C. A., Scott, A. I., Martens, J. H., Jahn, D., Thermes, C., Rambach, A. & Warren, M. J. (2003)
    Identification and functional analysis of enzymes required for precorrin-2 dehydrogenation and metal ion insertion in the biosynthesis of sirohaem and cobalamin in Bacillus megaterium.

    Biochem J. 370, 505-516


    PUBMED: 12519998
    Muench, R., Hiller, K., Barg, H., Heldt, D., Linz, S., Wingender, E. & Jahn, D. (2003)
    PRODORIC: Prokaryotic Database of Gene Regulation.

    Nucleic Acids Res. 31, 266-269


    PUBMED: 12520026
    Finking, R., Solsbacher, J, Konz, D., Schobert, M., Schafer, A., Jahn, D. & Marahiel, M. A. (2002)
    Characterization of a new type of phosphopantetheinyl transferase for fatty acid and siderophore synthesis in Pseudomonas aeruginosa.

    J. Biol. Chem. 277, 50293-50302


    PUBMED: 12196141
    Moser, J., Schubert, W. D., Heinz, D. W. & Jahn, D. (2002)
    Structure and function of glutamyl-tRNA reductase involved in 5-aminolaevulinic acid formation.

    Biochem. Soc. Trans. 30, 579-584


    PUBMED: 12073043
    Krieger, R., Rompf, A., Schobert, M. & Jahn, D. (2002)
    The Pseudomonas aeruginosa hemA promoter is regulated by Anr, Dnr, NarL and integration host factor.

    Mol. Gen. Genet. 267, 409-417


    Schubert, W. D., Moser, J. Schauer, S., Heinz, D. & Jahn, D. (2002)
    Structure and function of glutamyl-tRNA reductase, the first enzmye of tetrapyrrole biosynthesis in plants and prokaryotes.

    Photosynthesis Res., 74, 205-210


    PUBMED: 12370189
    Schauer, S., Chaturvedi, S., Randau, L., Moser, J., Kitabatake, M., Lorenz, S., Verkamp, E., Schubert, W. D., Nakayashiki, T., Murai, M., Wall, K., Thomann, H. U., Heinz, D. W., Inokuchi, H., Soell, D. & Jahn, D. (2002)
    Escherichia coli glutamyl-tRNA reductase: Trapping of the thioester intermediate.

    J. Biol. Chem., 277, 48657-48663


    Löhbach, C., Bakowsky, U., Kneuer, C., Jahn, D., Graeter, T., Schäfers, H.-J. & Lehr, C.-M. (2002)
    Wet chemical modification of PTFE implant surfaces with specific cell adhesion molecule.

    Chem. Comm. 21, 2568-2569


    PUBMED: 12114526
    Layer, G., Verfurth, K., Mahlitz, E. & Jahn, D. (2002)
    Oxygen-independent Coproporphyrinogen-III Oxidase HemN from Escherichia coli.


    J. Biol. Chem. 277, 34136-34142.


    PUBMED: 12196141
    Moser, J., Schubert, W. D., Heinz, D. W. & Jahn, D. (2002)
    Structure and function of glutamyl-tRNA reductase involved in 5-aminolaevulinic acid formation.

    Biochem. Soc. Transac. 30, 579-584


    PUBMED: 12079382
    Frere, F., Schubert, W. D., Stauffer, F., Frankenberg, N., Neier, R., Jahn, D. & Heinz, D. W. (2002)
    Structure of Porphobilinogen Synthase from Pseudomonas aeruginosa in Complex with 5-Fluorolevulinic Acid Suggests a Double Schiff Base Mechanism.

    J. Mol. Biol. 320, 237-247


    PUBMED: 11931560
    Schobert, M. & Jahn, D. (2002)
    Regulation of heme biosynthesis in non-phototrophic bacteria.

    J. Mol. Microbiol. Biotechnol. 4, 287-294. Review


    PUBMED: 11935176
    Martens, J.-H., Barg, H., Warren, M. J. & Jahn, D. (2002)
    Microbial Production of Vitamin B12.

    Appl. Microbiol. Biotechnol. 58, 275-285. Review


    PUBMED: 11726494
    Moser, J., Schubert, W., Beier, V., Bringemeier, I., Jahn, D. & Heinz, D. W. (2001)
    V-shaped Structure of Glutamyl-tRNA-Reductase, the first Enzyme of tRNA-Dependent Tetrapyrrole Biosynthesis.

    EMBO. J. 20, 6583-6590


    PUBMED: 11698370
    Marino, M., Cruz-Ramos, H., Hoffmann, T., Glaser, P. & Jahn, D. (2001)
    Modulation of Anaerobic Energy Metabolism of Bacillus subtilis by arfM (ywiD).

    J. Bacteriol. 183, 6815-6821


    PUBMED: 11931560
    Schobert, M. & Jahn, D. (2001)
    Regulation of Heme Biosynthesis in Bacteria.

    J. Mol. Microbiol. Biotechnol., 4, 287-294



    PUBMED: 10809684
    Cruz-Ramos, H., Hoffmann, T., Marino, M., Nedjari, H., Presecan-Siedel, E., Dreesen, O., Glaser, P. & Jahn, D. (2000)
    Fermentative metabolism of Bacillus subtilis: Physiology and regulation of gene expression.

    J. Bacteriol. 182, 3072-3080


    PUBMED: 10658656
    Marino, M., Hoffmann, T., Mobitz, H., Schmid, R. & Jahn, D. (2000)
    Changes in protein synthesis during the adaptation to anaerobic growth conditions in Bacillus subtilis.

    Microbiology 146, 97-105


    Jahn, D. (2000)
    Anpassungsfähigkeit von Mikroorganismen.

    In: Mikrobiologie - Lernbücher Biologie (K. Munk, Eds.). Spektrum, Akademischer Verlag



    PUBMED: 10498703
    Homuth, G., Rompf, A. , Schumann, W. & Jahn, D. (1999)
    Transcriptional control of Bacillus subtilis hemN and hemZ.

    J. Bacteriol. 181, 5922-5929


    PUBMED: 10521455
    Moser, J., Lorenz, S. , Hubschwerlen, C., Rompf, A. & Jahn, D. (1999)
    Methanopyrus kandleri glutamyl-tRNA reductase.

    J. Biol. Chem. 274, 30679-30685


    PUBMED: 10529244
    Frankenberg, N., Jahn, D. & Jaffe, E. (1999)
    Pseudomonas aeruginosa contains a novel type V porphobilinogen synthase with no required catalytic metal ions.

    Biochemistry 38, 13976-13982


    PUBMED: 10529243
    Frankenberg, N., Heinz, D.W. & Jahn, D. (1999)
    Production, purification and characterization of a Mg2+-responsive porphobilinogen synthase from Pseudomonas aeruginosa.

    Biochemistry 38, 13968-13975


    Frankenberg, N., Erskine, P.R., Cooper, J., Shoolingin-Jordan, P. M., Jahn, D. & Heinz, D. (1999)
    High resolution crystal structure of a magnesium-dependent 5-aminolevulinic acid dehydratase.

    J. Mol. Biol. 289, 591-602


    Easson, E., Haltner, E., Lehr, C.-M., & Jahn, D. (1999)
    Bacterial invasin factors as second generation bioadhesives.

    In: Bioadhesive drug delivery systems: Fundamentals, novel approaches, and developments (Mathiowitz, E., Lehr, C-M., Chickering, D., Eds.). Begell House, Inc., New York, 405-433


    Rompf, A. & Jahn, D. (1999)
    Ecology of bacteria and fungi in foods: Influence of redox potential and pH.

    In: Encyclopedia of Food Microbiology (Holland, T., Ed.), Academic Press Ltd., London, 556-562



    PUBMED: 9765565
    Nakano, M.M., Hoffmann, T., Zhu, Y. & Jahn, D. (1998)
    Nitrogen and oxygen regulation of Bacillus subtilis nasDEF encoding NADH-dependent nitrite reductase by TnrA and ResDE.

    J. Bacteriol. 180, 5344-5350


    Rajendran, N., Rompf, A., Marahiel, M.A. & Jahn, D. (1998)
    Isolation and characterization of a transposon mutant of Pseudomonas fluorescens AU63 deficient in antifungal activity against Pythium ultimum.

    Let. Appl. Microbiol. 27, 152-157


    PUBMED: 9732527
    Rompf, A., Schmid, R. & Jahn, D. (1998)
    Changes in protein expression as a conseqeunce of heme depletion in Escherichia coli.

    Curr. Microbiol. 37, 226-230


    PUBMED: 9767567
    Rompf, A., Hungerer, C., Hoffmann, T., A., Lindenmeyer, M., Romling, U., Gross, U., Doss, M.O., Arai, H., Igarashi, Y. & Jahn, D. (1998)
    Regulation of Pseudomonas aeruginosa hemN and hemF by the dual action of the redox response regulators Anr and Dnr.

    Mol. Microbiol. 29, 985-997


    PUBMED: 9529530
    Frankenberg, N., Hungerer, C., Kittel, T. & Jahn, D. (1998)
    Cloning and characterisation of the Pseudomonas aeruginosa hemB encoding a magnesium-dependent aminolevulinic acid dehydratase.

    Mol. Gen. Genet. 257, 485-489


    PUBMED: 9396835
    Lieb, C., Siddiqui, R. A., Hippler, B., Jahn, D. & Friedrich, B. (1998)
    The Alcaligenes eutrophus hemN gene encoding the oxygen-independent coproporphyrinogen III oxidase is required for heme biosynthesis during anaerobic growth.

    Arch. Microbiol. 169, 52-60


    PUBMED: 9422613
    Hoffmann, T., Frankenberg, N., Marino, M. & Jahn, D. (1998)
    Ammonification in Bacillus subtilis utilizing dissimilatory nitrite reductase is dependent on resDE.

    J. Bacteriol. 180, 186-189


    PUBMED: 9371469
    Hippler, B., Homuth, G., Hoffmann, T., Schumann, W. & Jahn, D. (1997)
    Characterization of Bacillus subtilis hemN.

    J. Bacteriol. 179, 7181-7185


    PUBMED: 9294458
    Moebius, E., Jahn, M., Schmid, R., Jahn, D. & Maser, E. (1997)
    Testosterone regulated expression of enzymes involved in steroid and aromatic hydrocarbon catabolism in Comamonas testosteroni.

    J. Bacteriol. 179, 5951-5955


    Jahn, D. (1997)
    Enzymatik und Regulation der Bildung bakterieller Tetrapyrrole.

    Colloquia Academica der Akademie der Wissenschaften und Literatur Mainz, 43-74


    Easson, J.H., Hungerer, C., Jahn, D. & Lehr, C.-M. (1996)
    Bioinvasive drug carrier systems for oral delivery of peptides and proteins.

    Proc. Intern. Control Rel. Bioact. Mater. 23, 1000-1001


    PUBMED: 8831980
    Hungerer, C., Weiss, D., Thauer, R.K. & Jahn, D. (1996)
    Cloning, characterization and expression of the Methanobacterium thermoautotrophicum hemA gene encoding glutamyl-tRNA reductase.

    Bioorg. Med. Chem. 7, 1089-1095


    Jahn, D., Hungerer, C. & Troup, B. (1996)
    Ungewöhnliche Schritte und umweltregulierte Gene der bakteriellen Hämbiosynthese.

    Naturwissenschaften 83, 389-400. Review


    Jahn, D., Hungerer, C. & Troup, B. (1996)
    Die bakterielle Hämbiosynthese: Alternative Wege und umweltgesteuerte Genexpression.

    Biospektrum 2, 22-27


    PUBMED: 7557333
    Hoffmann, T., Troup, B., Szabo, A., Hungerer, C. & Jahn, D. (1995)
    The anaerobic life of Bacillus subtilis. Cloning and characterization of the genes encoding the respiratory nitrate reductase system.

    FEMS Microbiol. Let. 131, 219-225


    PUBMED: 7565600
    Hungerer, C., Troup, B., Romling, U. & Jahn, D. (1995)
    Cloning, mapping and characterization of the Pseudomonas aeruginosa hemL gene.

    Mol. Gen. Genet. 248, 375-380


    PUBMED: 7768836
    Troup, B., Hungerer, C. & Jahn, D. (1995)
    Cloning and characterization of the Escherichia coli hemN gene encoding the oxygen- independent coproporphyrinogen III oxidase.

    J. Bacteriol. 177, 3326-3331


    PUBMED: 7883699
    Hungerer, C., Troup, B., Romling, U. & Jahn, D. (1995)
    Regulation of the hemA gene during 5-aminolevulinic acid formation in Pseudomonas aeruginosa.

    J. Bacteriol. 177, 1435-1443


    PUBMED: 8300522
    Troup, B., Jahn, M., Hungerer, C. & Jahn, D. (1994)
    Isolation of the hemF operon containing the gene for the Escherichia coli aerobic coproporphyrinogen III oxidase by in vivo complementation of a yeast HEM13 mutant.

    J. Bacteriol. 176, 673-680


    PUBMED: 8138133
    Rajendran, N., Jahn, D., Jayaraman, K. & Marahiel, M.A. (1994)
    Transposon Tn5 mutagenesis of Pseudomonas fluorescens to isolate mutants deficient in antibacterial activity.

    FEMS Microbiol. Let. 115, 191-196


    Jahn, D., Verkamp, E. & Soell, D (1992)
    Glutamyl-transfer RNA: a precursor of heme and chlorophyll biosynthesis.

    Trends Biol. Sci. 17, 215-219. Review



    12(6), 1719–1733

    Haddad, I., Münch, R. & Jahn, D. (2010)

    Vorrichtung und System zur Durchführung von zeitaufgelösten Untersuchungen an Zellproben
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    Malten, M. & Jahn, D. (2003).

    Produktion und Sekretion von Glucosyltransferasen.
    DE: 102 25 380.3


    Barg, H. & Jahn, D. (2003).

    Verbessertes Verfahren zur Herstellung von Vitamin B12
    DE 103 00 719.9


    Barg, H., Warren, M. J., Künkel, A. & Jahn, D. (2002).

    Verbessertes Verfahren zur Herstellung von Vitamin B12
    DE 102 93 795.8


    Barg, H., Warren, M. J., Künkel, A. & Jahn, D. (2002).

    Verbessertes Verfahren zur Herstellung von Vitamin B12
    DE 101 50 323.7


    Barg, H., Martens, J.-H., Warren, M. J., Künkel, A. & Jahn, D. (2001).

    Optimierte Verfahren zur Herstellung von Vitamin B12 mit Bacillus megaterium.
    DE 101 50 359.8


    Martens, J.-H., Barg, H., Warren, M. J., Künkel, A. & Jahn, D. (2001).

    Verfahren zur Herstellung von Vitamin B12 mit Bacillus megaterium.
    DE 101 50 323.7

    12(6), 1719–1733

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