Cross-sectional Group 6 - Pharmaceutical Manufacturing Engineering

Working towards the Pharmaceutical Factory of the Future this cross-sectional group takes a comprehensive approach to establish sustainable production technologies for pharmaceutical drugs and dosage forms based on the processes developed in Departments 1 to 3. Special focus is on scale-up, continuous manufacturing, packaging technology, efficient use of energy and resources in production, and life cycle engineering (costs and environmental impacts).

This group aims to elaborate, assess, optimize and provide a customized production technology taking into account the specific regulatory, plant-specific, infrastructural and operational conditions of a pharmaceutical production in the scale that the PVZ provides.

From 2020 onwards flexible, integrated and tailored production concepts from drug extraction or biotechnological or chemical drug synthesis to packaged medicines for a fixed capacity shall be designed and evaluated. This includes the implementation of instruments and plant technology together with process management, analytics, quality control based on models and parameters, and quality assurance as well as aspects on regulation and operating technology.

Furthermore, adequate methods and tools for an early-stage economic as well as ecological assessment support the sustainability-oriented planning and design of processes, process chains, facilities and plants. Depending on the demands of the product and the capacity the ideal production technology can be identified, adapted and assessed.

left: Microfluidic system to rpoduce nanoparticle medical ingredients; mixing dilutions with gas segments; right: Manufacturing of colloidal drug carrier systems by premix membrane emulsification



Heads of cross-sectional group:

Prof. Dr. rer. nat. Heike Bunjes | TU Braunschweig
Institut für Pharmazeutische Technologie
Mendelssohnstr. 1 | 38106 Braunschweig
E-Mail: heike.bunjes@tu-braunschweig.de | Phone: +49 (0)531 391-5662

Prof. Dr.-Ing. Christoph Herrmann | TU Braunschweig
Institut für Werkzeugmaschinen und Fertigungstechnik
Langer Kamp 19 B | 38106 Braunschweig
E-Mail: c.herrmann@tu-braunschweig.de | Phone: +49 (0)531 391-7149

  last changed 20.12.2016
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