Yannic Nonnenmacher

Yannic Nonnenmacher
PhD Student
Room 136 (BRICS)
Tel.:+49 (0) 531-391-55166

2014 - now
PhD StudentUniversity of Luxemburg and TU BraunschweigHiller Lab

2011 - 2014
Biotechnology, Saarland University, Germany
Degree: Master of Science

2008 - 2011
Human and Molecular Biology, Saarland University, Germany
Degree: Bachelor of Science



  • Nonnenmacher Y., Hiller K. (2018) Biochemistry of Proinflammatory Macrophage Activation. Cellular and Molecular Life Sciences, 10.1007/s00018-018-2784-1

  • Hollishead K.E.R., Munford H., Eales K.L., Bardella C., Li C., Escribano-Gonzales C., Thakker A., Nonnenmacher Y., Kluckova K., Jeeves M., et al., (2018) Oncogenic IDH1 Mutations Promote Enhanced Proline Synthesis through PYCR1 to Support the Maintenance of Mitochondrial Redox Homeostasis. Cell Reports, 10.1016/j.celrep.2018.02.084

  • Raffel S., Falcone M., Kneisel N., Hansson J., Wang W., Lutz C., Bullinger L., Poschet G., Nonnenmacher Y., Barnert A., et al., (2017) BCAT1 restricts αkG levels in AML stem cells leading to IDHmut-like DNA hypermethylation. Nature, 10.1038/nature24294

  • Santos Silva L., Poschet G., Nonnenmacher Y., Becker, H.M., Sapcariu S., Gaupel A.C., Schlotter M., Wu Y., Kneisel N., Seiffert M., et al., (2017) Branched‐chain ketoacids secreted by glioblastoma cells via MCT1 modulate macrophage phenotype. EMBO Reports, 10.15252/embr.201744154

  • Mak T.W., Grusdat M., Duncan G.S., Dostert C., Nonnenmacher Y., Cox M., Binsfeld C., Hao Z., Brüstle A., Itsumi M., et al., (2017) Glutathione Primes T Cell Metabolism for Inflammation. Immunity, 10.1016/j.immuni.2017.06.009

  • Nonnenmacher Y., Palorini R., Fouquier d'Herouël A., Krämer L., Neumann-Schaal M., Chiaradonna F., Skupin A., Wegner A., and Hiller K. (2016) Analysis of mitochondrial metabolism in situ: Combining stable isotope labeling with selective permeabilization. Metabolic Engineering, 10.1016/j.ymben.2016.12.005

  • Ullmann P., Qureshi-Baig K., Rodriguez F., Ginolhac A., Nonnenmacher Y., Ternes D., Weiler J., Gäbler K., Bahlawane C., Hiller K., et al., (2016) Hypoxia-responsive miR-210 promotes self-renewal capacity of colon tumor-initiating cells by repressing ISCU and by inducing lactate production. Oncotarget, 10.18632/oncotarget.11772.

  • Delcambre S., Nonnenmacher Y., and Hiller K. (2016) Dopamine Metabolism and Reactive Oxygen Species Production. Book chapter, Mitochondrial Mechanisms of Degeneration and Repair in Parkinson's Disease, 10.1007/978-3-319-42139-1_2

  • Meiser J., Delcambre S., Wegner A., Jäger C., Ghelfi J., Fouquier d'Herouël A., Dong X., Weindl D., Stautner C., Nonnenmacher Y., et al., (2016) Loss of DJ-1 impairs antioxidant response by altered glutamine and serine metabolism. Neurobiology of Disease, 10.1016/j.nbd.2016.01.019

  • Nicolae A., Wahrheit J., Nonnenmacher Y., Weyler C., and Heizle E. (2015) Identification of active elementary flux modes in mitochondria using selectively permeabilized CHO cells. Metabolic Engineering, 10.1016/j.ymben.2015.09.014

  • Wahrheit J., Nonnenmacher Y., Sperber S., and Heinzle E. (2015) High-throughput respiration screening of single mitochondrial substrates using permeabilized CHO cells highlights control of mitochondria metabolism. Engineering in Life Sciences, 10.1002/elsc.201400175

  • Niklas J., Nonnenmacher Y., Rose T., Sandig V., and Heinzle E. (2011) Quercetin treatment changes fluxes in the primary metabolism and increases culture longevity and recombinant α1-antitrypsin production in human AGE1.HN cells. Applied Microbiology and Biotechnology, 10.1007/s00253-011-3811-4.

  aktualisiert am 03.04.2018
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