Yannic Nonnenmacher

Yannic Nonnenmacher
PhD Student
Room 136 (BRICS)
Tel.:+49 (0) 531-391-55166

2014 - now
PhD StudentUniversity of Luxemburg and TU BraunschweigHiller Lab

2011 - 2014
Biotechnology, Saarland University, Germany
Degree: Master of Science

2008 - 2011
Human and Molecular Biology, Saarland University, Germany
Degree: Bachelor of Science


  • Niklas J., Nonnenmacher Y., Rose T., Sandig V., and Heinzle E. (2011). Quercetin treatment changes fluxes in the primary metabolism and increases culture longevity and recombinant α1-antitrypsin production in human AGE1.HN cells. Applied Microbiology and Biotechnology, 10.1007/s00253-011-3811-4.

  • Wahrheit J., Nonnenmacher Y., Sperber S., and Heinzle E. (2015). High-throughput respiration screening of single mitochondrial substrates using permeabilized CHO cells highlights control of mitochondria metabolism. Engineering in Life Sciences, 10.1002/elsc.201400175

  • Nicolae A., Wahrheit J., Nonnenmacher Y., Weyler C., and Heizle E. (2015). Identification of active elementary flux modes in mitochondria using selectively permeabilized CHO cells. Metabolic Engineering, 10.1016/j.ymben.2015.09.014

  • Meiser J., Delcambre S., Wegner A., Jäger C., Ghelfi J., Fouquier d'Herouël A., Dong X., Weindl D., Stautner C., Nonnenmacher Y., et al., (2016). Loss of DJ-1 impairs antioxidant response by altered glutamine and serine metabolism. Neurobiology of Disease, 10.1016/j.nbd.2016.01.019

  • Delcambre S., Nonnenmacher Y., and Hiller K. (2016). Dopamine Metabolism and Reactive Oxygen Species Production. Book chapter, Mitochondrial Mechanisms of Degeneration and Repair in Parkinson's Disease, 10.1007/978-3-319-42139-1_2

  • Ullmann P., Qureshi-Baig K., Rodriguez F., Ginolhac A., Nonnenmacher Y., Ternes D., Weiler J., Gäbler K., Bahlawane C., Hiller K., et al., (2016). Hypoxia-responsive miR-210 promotes self-renewal capacity of colon tumor-initiating cells by repressing ISCU and by inducing lactate production. Oncotarget, 10.18632/oncotarget.11772.

  • Nonnenmacher Y., Palorini R., Fouquier d'Herouël A., Krämer L., Neumann-Schaal M., Chiaradonna F., Skupin A., Wegner A., and Hiller K. (2016). Analysis of mitochondrial metabolism in situ: Combining stable isotope labeling with selective permeabilization. Metabolic Engineering, 10.1016/j.ymben.2016.12.005

  • Mak T.W., Grusdat M., Duncan G.S., Dostert C., Nonnenmacher Y., Cox M., Binsfeld C., Hao Z., Brüstle A., Itsumi M., et al., (2017). Glutathione Primes T Cell Metabolism for Inflammation. Immunity, 10.1016/j.immuni.2017.03.019

  • L. Silva, G. Poschet, Y. Nonnenmacher, H. Becker, S. Sapcariu, A. Gaupel, M. Schlotter, Y. Wu, N. Kneisel, M. Seiffert, et al., (2017). Branched-chain ketoacids secreted by glioblastoma cells via MCT1 modulate macrophage phenotype. EMBO Reports, 10.15252/embr.201744154

  • S. Raffel, N. Kneisel, M. Falcone, J. Hansson, W. Wang, C. Lutz, L. Bullinger, G. Poschet, Y. Nonnenmacher, A. Barnert, et al., (accepted). BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation. Nature,

  aktualisiert am 17.11.2017
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