Dr. Andre Wegner

Dr. Andre Wegner
Research Group Leader
Room 143 (BRICS)
Tel.:+49 (0) 531-391-55203


Since 2016
Group Leader of Pathometabolism group, TU Braunschweig
Topics: Pathological alterations of mammalian metabolism, computational modeling of human metabolism

Postdoc, University of Luxembourg
Topics: Analysis of human metabolism using stable-isotopes

Visiting scholar, Massachusetts Institute of Technology, Department of Chemical Engineering
Topics: 13C-Metabolic Flux Analysis

Graduate student, University of Luxembourg
Topics: Mass-Spectrometry, Human Metabolism, Stable-Isotope Labelling
PhD thesis: Computational tools for mass spectrometry based metabolic profiling

2003 – 2010
Study of Bioinformatics and Computer Science, University of Tuebingen


Google scholar


  • Nonnenmacher, Y., Palorini R., Fouquier d'Herouel, A., Krämer, L., Neumann-Schaal, M., Chiaradonna, F., W., Skupin, A., Wegner, A., Hiller, K.
    Analysis of mitochondrial metabolism in situ: Combining stable isotope labeling with selective permeabilization.
    Metab Eng. 2017 Sep;43(Pt B):147-155


  • Weindl D, Wegner A., Hiller K.
    MIA: non-targeted mass isotopolome analysis.
    Bioinformatics. 2016 Sep 15;32(18):2875-6.
  • Weindl D, Cordes T, Battello N, Sapcariu SC, Dong X, Wegner A, Hiller K.
    Bridging the gap between non-targeted stable isotope labeling and metabolic flux analysis.
    Cancer Metab. 2016 Apr 23;4:10.
  • Battello N, Zimmer AD, Goebel C, Dong X, Behrmann I, Haan C, Hiller K, Wegner A
    The role of HIF-1 in oncostatin M-dependent metabolic reprogramming of hepatic cells.
    Cancer Metab. 2016 Feb 17;4:3.


  • Weindl D, Wegner A, Hiller K.
    Metabolome-Wide Analysis of Stable Isotope Labeling-Is It Worth the Effort?
    Front Physiol. 2015 Nov 20;6:344.

  • Venturelli S, Belz RG, Kämper A, Berger A, von Horn K, Wegner A, Böcker A, Zabulon G, Langenecker T, Kohlbacher O, Barneche F, Weigel D, Lauer UM, Bitzer M, Becker C.
    Plants Release Precursors of Histone Deacetylase Inhibitors to Suppress Growth of Competitors.
    Plant Cell. 2015 Nov;27(11):3175-89.
  • Weindl D, Wegner A, Hiller K.
    Non-targeted Tracer Fate Detection.
    Methods Enzymol. 2015;561:277-302.
  • Weindl D, Wegner A, Jäger C, Hiller K.
    Isotopologue ratio normalization for non-targeted metabolomics.
    J Chromatogr A. 2015 Apr 10;1389:112-9.
  • Wegner A, Meiser J, Weindl D, Hiller K.
    How metabolites modulate metabolic flux.
    Curr Opin Biotechnol. 2015 Aug;34:16-22.


  • Wegner A, Weindl D, Jäger C, Sapcariu SC, Dong X, Stephanopoulos G, Hiller K.
    Fragment formula calculator (FFC): determination of chemical formulas for fragment ions in mass spectrometric data.
    Anal Chem. 2014 Feb 18;86(4):2221-8.


  • McGuirk S, Gravel SP, Deblois G, Papadopoli DJ, Faubert B, Wegner A, Hiller K, Avizonis D, Akavia UD, Jones RG, Giguère V, St-Pierre J.
    PGC-1α supports glutamine metabolism in breast cancer.
    Cancer Metab. 2013 Dec 5;1(1):22.

  • Michelucci A, Cordes T, Ghelfi J, Pailot A, Reiling N, Goldmann O, Binz T, Wegner A, Tallam A, Rausell A, Buttini M, Linster CL, Medina E, Balling R, Hiller K.
    Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production.
    Proc Natl Acad Sci U S A. 2013 May 7;110(19):7820-5.
  • Wegner A, Sapcariu SC, Weindl D, Hiller K.
    Isotope cluster-based compound matching in gas chromatography/mass spectrometry for non-targeted metabolomics.
    Anal Chem. 2013 Apr 16;85(8):4030-7.
  • Hiller K, Wegner A, Weindl D, Cordes T, Metallo CM, Kelleher JK, Stephanopoulos G.
    NTFD--a stand-alone application for the non-targeted detection of stable isotope-labeled compounds in GC/MS data.
    Bioinformatics. 2013 May 1;29(9):1226-8.

  last changed 12.12.2017
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