Dr. Antje Chang

Dr. Antje Chang
Senior Scientist
Room 139 (BRICS)
Tel.:+49 (0) 531-391-55206

Since 03/2018
Senior Scientist at the Department of Bioinformatics & Biochemistry (BRENDA database), TU Braunschweig

11/2004 – 02/2018
Senior Executive at the Enzymeta GmbH (BRENDA database), Erftstadt

06/1998 – 10/2004
Postdoc, Institute for Biochemistry, Universität zu Köln (BRENDA database)

11/1993 – 12/1997
Graduate Student, Institute for Pharmaceutical Biology, TU Braunschweig, Prof. Dr. Thomas Hartmann
PhD thesis: „Identification, solubilization, and characterization of a membrane-bound, specific pyrrolizidin-alkaloid-N-oxygenase aus seedlings from Crotalaria scassellatii“

04/1993 – 10/1993
Intership at the Development Center for Biotechnology (DCB) Taipei/Taiwan and student at the Mandarin Training Center at the National Taiwan Normal University

10/1987 – 04/1993
Studies in Biology, TU Braunschweig
Degree: Diplom
Diploma thesis, Insitute for Pharmaceutical Biology, TU Braunschweig: „Biochemische und physiologische Charakterisierung der S-Adenosyl-L-methionin:4-Hydroxy-3(3-methyl-2-butenyl)-2-chinolon O-Methyltransferase des Furochinolin-Biosyntheseweges aus Ruta graveolens“


  1. Jeske, L., Placzek, S., Schomburg, I., Chang, A., Schomburg, D.
    BRENDA in 2019: a European ELIXIR core data resource (2019) Nucleic Acids Research, 47 (D1), D542-D549.

  2. Schomburg, I., Jeske, L., Ulbrich, M., Placzek, S., Chang, A., Schomburg, D.
    The BRENDA enzyme information system - From a database to an expert system. (2017) Journal of Biotechnology, 261, 194-206.

  3. Placzek, S., Schomburg, I., Chang, A., Jeske, L., Ulbrich, M., Tillack, J., Schomburg, D.
    BRENDA in 2017: New perspectives and new tools in BRENDA. (2017) Nucleic Acids Research, 45 (D1), D380-D388.

  4. Chang, A., Schomburg, I., Placzek, S., Jeske, L., Ulbrich, M., Xiao, M., Sensen, C.W., Schomburg, D.
    BRENDA in 2015: Exciting developments in its 25th year of existence. (2015) Nucleic Acids Research, 43 (D1), D439-D446. Schomburg, I., Chang, A., Schomburg, D.
    25 Jahre BRENDA. BRENDA – das Portal zur Welt der Enzyme. (2014) Biospektrum, 06.14, 700-702.

  5. Schomburg, D., Schomburg, I., Chang, A.
    Springer handbook of enzymes: second edition. (2001-2013) Springer Handbook of Enzymes

  6. Schomburg, I., Chang, A., Placzek, S., Söhngen, C., Rother, M., Lang, M., Munaretto, C., Ulas, S., Stelzer, M., Grote, A., Scheer, M., Schomburg, D.
    BRENDA in 2013: Integrated reactions, kinetic data, enzyme function data, improved disease classification: New options and contents in BRENDA. (2013) Nucleic Acids Research, 41 (D1), pp. D764-D772

  7. Michal, G. Schomburg, D. (editors)
    Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology. Buchkapitel 3.13. "Plant Secondary Metabolism" Antje Chang. (2012), 193-209

  8. Söhngen, C., Chang, A., Schomburg, D.
    Development of a classification scheme for disease-related enzyme information. (2011) BMC Bioinformatics, 12, 329.

  9. Gremse, M., Chang, A., Schomburg, I., Grote, A., Scheer, M., Ebeling, C., Schomburg, D.
    The BRENDA Tissue Ontology (BTO): The first all-integrating ontology of all organisms for enzyme sources. (2011) Nucleic Acids Research, D507-D513.

  10. Scheer, M., Grote, A., Chang, A., Schomburg, I., Munaretto, C., Rother, M., Söhngen, C., Stelzer, M., Thiele, J., Schomburg, D.
    BRENDA, the enzyme information system in 2011. (2011) Nucleic Acids Research, 39,D670-D676.

  11. Chang, A., Scheer, M., Grote, A., Schomburg, I., Schomburg, D.
    BRENDA, AMENDA and FRENDA the enzyme information system: New content and tools in 2009. (2009) Nucleic Acids Research, 37, D588-D592. Cited 268 times.

  12. Barthelmes, J., Ebeling, C., Chang, A., Schomburg, I., Schomburg, D.
    BRENDA, AMENDA and FRENDA: The enzyme information system in 2007. (2007) Nucleic Acids Research, 35, D511-D514.

  13. Schomburg, I., Chang, A., Ebeling, C., Gremse, M., Heldt, C., Huhn, G., Schomburg, D.
    BRENDA, the enzyme database: Updates and major new developments. (2004) Nucleic Acids Research, 32, D431-D433.

  14. Schomburg, I., Chang, A., Schomburg, D.
    BRENDA, enzyme data and metabolic information. (2002) Nucleic Acids Research, 30, 47-49.

  15. Schomburg, I., Chang, A., Hofmann, O., Ebeling, C., Ehrentreich, F., Schomburg, D.
    BRENDA: A resource for enzyme data and metabolic information. (2002) Trends in Biochemical Sciences, 27, 54-56.

  16. Chang, A., Hartmann, T.S
    Solubilization and characterization of a senecionine N-oxygenase from Crotalaria scassellatii seedlings. (1998) Phytochemistry, 49, 1859-1866.

  last changed 26.03.2019
TU_Icon_E_Mail_1_17x17_RGB pagetop