The department is located at the Biocenter of the Technical University at Brunswick. Our research focuses on the genetic control mechanisms of vertebrate development using mouse and chicken as model organisms. Specifically, we are interested in genes and signals governing heart and skeletal muscle development, left-right asymmetry, segmentation of the vertebrate body axis (somitogenesis), and various aspects of organ development involving NKX transcription factors. Moreover, we try to identify novel developmental control genes by suitable screening methods including gene traps in mouse. All techniques of modern Molecular- and Cell Biology, and reverse genetics in mice are available including transgenics and targeted gene disruption. The long term goal is to understand molecular causes of human hereditary diseases and malfunctions in order to develop rational strategies for cure.
These webpages are under construction at the moment. New content will be made available soon. .
Responsible:
Dr. Barbara Winter
Feedback to molbio@tu-braunschweig.de
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