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2010 |
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Peer viewed articles |
David, F., Westphal, R., Bunk, B., Jahn, D. & Franco-Lara, E. (2010)
Optimization of antibody fragment production in Bacillus megaterium: the role of metal ions on protein secretion.
J Biotechnol. in press
Haffke, M., Menzel, A., Carius, Y., Jahn, D. & Heinz, D.W. (2010)
Structures of the nucleotide-binding domain of the human ABCB6 transporter and its complexes with nucleotides.
Acta Cryst. in press
Rosenau, F., Isenhardt, S., Gdynia, A., Tielker, D., Schmidt, E., Tielen, P., Schobert, M., Jahn, D., Wilhelm, S. & Jaeger, K.E. (2010)
Lipase LipC affects motility, biofilm formation and rhamnolipid production in Pseudomonas aeruginosa.
FEMS Microbiol Lett. in press
PUBMED: 20596705
Stammen, S., Schuller, F., Dietrich, S., Gamer, M., Biedendieck, R. & Jahn, D. (2010)
Application of Escherichia coli phage K1E DNA-dependent RNA polymerase for in vitro RNA synthesis and in vivo protein production in Bacillus megaterium.
Appl. Microbiol. Biotechnol. 88: 529-539
PUBMED: 20553007
Silva, P., Schulz, C., Jahn, M., Jahn, D. & Ramos, M. (2010)
A Tale of two acids: When arginine is a more appropriate acid than H3O+.
J Phys Chem 114: 8994-9001
PUBMED: 20558746
Bröcker, M., Schomburg, S., Heinz, D.W., Jahn, D., Schubert, W.D. & Moser, J. (2010)
Crystal structure of the nitrogenase-like dark operative protochlorophyllide oxidoreductase catalytic complex (ChlN/ChlB)2.
J. Biol Chem in press.
PUBMED: 20484676
Möbius, K., Arias-Cartin, R., Breckau, D., Haennig, A.-L., Riedmann, K., Biedendieck, R., Schroeder, S., Becher, D., Magalon, A., Moser, J., Jahn, M. & Jahn, D. (2010)
Heme biosynthesis is coupled to electron transport chains for energy generation
Proc. Natl. Acad. Sci. USA 107,10436-10441.
PUBMED: 20435764
Stammen, S., Müller, B.K., Korneli, C., Biedendieck, R., Gamer, M., Franco-Lara, E. & Jahn, D. (2010)
High yield intra- and extracellular protein production using Bacillus megaterium
Appl. Environ. Microbiol. 76: 4037-4046
PUBMED: 20506125
Layer, G., Reichelt, J., Jahn, D. & Heinz, D.W. (2010)
Structure and function of enzymes in heme biosynthesis
Protein Science 19, 1137-1161
Trunk, K., Benkert, B., Quaeck, N., Muench, R., Scheer, M., Garbe, J., Jaensch, J., Trost, M., Wehland, J., Buer, J., Jahn, M., Schobert, M. & Jahn, D. (2010)
Anaerobic adaptation in Pseudomonas aeruginosa: Definition of the Anr and Dnr Regulons.
Environ. Microbiol. 12, 1719-1733
PUBMED: 20075073
Bröcker, M., Wätzlich, D., Saggu, M., Lendzian, F., Moser, J. & Jahn, D. (2010)
Biosynthesis of (bacterio)chlorophylls: ATP-dependent transient subunit interaction and electron transfer of dark operative protochlorophyllide oxidoreductase.
J. Biol Chem 285: 8268-8277
Bunk, B., Schulz, A., Stammen, S., Münch, R., Warren, M. J., Rohde, M., Jahn, D. & Biedendieck, R. (2010)
A short story about a big magic bug.
Bioengineered Bugs 1: 1-7
Biedendieck, R., Malten, M., Barg, H., Bunk, B., Martens, J.-H., Deery, E., Leech, H., Warren, M. J. & Jahn, D. (2010)
Metabolic engineering of cobalamin (vitamin B12) production in Bacillus megaterium.
Microbial Biotechnology 3: 24–37
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Book articles and Reviews |
PUBMED: 20140656
Biedendieck, R., Bunk, B., Fürch, T., Franco-Lara, E., Jahn, M. & Jahn, D. (2010)
Systems Biology of Recombinant Protein Production in Bacillus megaterium in "Advances in Biochemical Engineering / Biotechnology"
(Scheper, T., Ed.); Vol. 113 - Biosystems Engineering (Wittmann, C., Ed.)
Springer, Berlin, Heidelberg in press
Layer, G., Jahn, D., Deery, E., Lawrence, A.D. & Warren, M. (2010)
Biosynthesis of heme and vitamin B12 in "Comprehensive natural products II Chemistry and Biology"
(Mander, L., Lui, H.-W.)
Elsevier: Oxford; 7:445–499
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2009 |
|
Peer viewed articles |
PUBMED: 20021642
Piekarski, T., Buchholz, I., Drepper, T., Schobert, M., Wagner-Doebler,
Genetic tools for the investigation of Roseobacter clade bacteria.
BMC Microbiology, 9: 265
PUBMED: 19822707
Heinemann, I.U., Schulz, C., Schubert, W.D., Heinz, D., Wang, Y.G., Kobashi, Y., Awa, Y., Wachi, M., Jahn, D. & Jahn, M. (2009)
Structure of the heme biosynthetic Pseudomonas aeruginosa porphobilinogen synthase in complex with the antibiotic alaremycin.
Antimicrobial Agents and Chemotherapy 54: 267-572
PUBMED: 19741735
Wagner-Döbler, I., Ballhausen, B., Baumgart, M., Brinkhoff, T., Buchholz, I., Bunk, B., Cypionka, H., Daniel, R., Drepper, T., Gerdts, G., Hahnke, S., Han, C., Jahn, D., Kalhoefer, D., Kiss, H., Klenk, H.-P., Kyrpides, N., Liebl, W., Liesegang, H., Meincke, L., Pati, A., Petersen, J., Piekarski, T., Pommerenke, C., Pradella, S., Pukall, R., Rabus, R., Stackebrandt, E., Thole, S., Thompson, L., Tielen, P., Tomasch, J., von Jan, M., Wanphrut, N., Wichels, A., Zech, H. & Simon, M. (2009)
The complete genome sequence of the algal symbiont Dinoroseobacter shibae; a hitchhiker`s guide to life in the sea.
ISME Journal 4:61-77
Beine, R., Valente, A.R., Biedendieck, R., Jahn, D. & Seibel, J. (2009)
Directed optimization of biocatalytic transglycosylation processes by the integration of genetic algorithms and fermentative approaches into a kinetic model.
Process Biochemistry 44: 1103–1114
PUBMED: 19336405
Wätzlich, D., Bröcker, M., Uliczka, F., Ribbe, M., Virus, S.; Jahn, D. & Moser, J. (2009)
Chimeric nitrogenase-like enzymes of (bacterio)chlorophyll biosynthesis.
J. Biol Chem 284:15530-15540
PUBMED: 20109147
Haddad, I., Hiller, K., Frimmersdorf, E., Benkert, B., Schomburg, D. & Jahn, D. (2009)
An Emergent Self-organizing Map Based Analysis Pipeline for Comparative Metabolome Studies.
In Silico Biology 9:149-162
PUBMED: 19308404
Gamer, M., Froede, D., Biedendieck, R., Stammen, S. & Jahn, D. (2009)
A T7 RNA polymerase-dependent gene expression system for Bacillus megaterium.
Appl Microbiol Biotechnol. 82:1195-1203
PUBMED: 19087229
Klein, S., Lorenzo, C., Hoffmann, S., Walther, J. M., Storbeck, S., Piekarski, T., Tindall, B. J., Wray, V., Nimtz, M. & Moser, J. (2009)
Adaptation of Pseudomonas aeruginosa to various conditions includes tRNA-dependent formation of alanyl-phosphatidylglycerol.
Mol Microbiol 71:551-565
PUBMED: 18974177
Grote, A., Klein, J., Retter, I., Haddad, I., Behling, S., Bunk, B., Biegler, I., Yarmolinetz, S., Jahn, D. & Münch, R. (2009)
PRODORIC (release 2009): a database and tool platform for the analysis of gene regulation in prokaryotes.
Nucleic Acids Res. Database issue D61-5
PUBMED: 19025572
Walther, J., Bröcker, M., Wätzlich, D., Nimtz, M., Rohde, M., Jahn, D. & Moser, J. (2009)
Protochlorophyllide: A new photosensitizer for the photodynamic inactivation of Gram-positive and Gram-negative bacteria.
FEMS Microbiol. Lett. 296:156-163
PUBMED: 18854354
Klein, J., Münch, R., Biegler, I., Haddad, I., Retter, I. & Jahn, D. (2009)
Strepto-DB, a database for comparative genomics of group A (GAS) and B (GBS) streptococci, implemented with the novel database platform ‘Open Genome Resource’ (OGeR)
Nucleic Acids Res. Database issue D494-8
|
Book articles and Reviews |
Jahn, D. & Heinz, D.W. (2009)
Biosynthesis of 5-aminolevulinic acid
in Tetrapyrroles-Birth, life and death (Warren, M.J., Smith, A. G., Eds.)
Landes Bioscience, Austin, Texas, USA
Tielen, P., Hogardt, M., Schobert, M., Heesemann, J., & Jahn, D. (2009)
Systembiologie der Harnwegs- und Wundinfektion durch Pseudomonas aeruginosa
GENOMEXPRESS 3.09, 17-19
Schilling, M., Hempel, D.C., & Jahn, D. (2009)
Vom Gen zum Produkt - aber mit System
Spektrum der Wissenschaft 10/09, 34-41
Jahn, D., & Schomburg, D. (2009)
Quo vadis Systembiologie
BIOspektrum 15, 07.09, 810-811
Bunk, B., Biedendieck, R., Jahn, D. & Vary, P. S. (2009)
Bacillus megaterium and other Bacilli, Industrial Applications
in "Encyclopedia of Industrial Biotechnology"
(Flickinger, M. C., Ed.)
Wiley, in press
Jahn, M. & Jahn, D. (2009)
Regulation und Systembiologie in "Taschenlehrbuch Biologie - Genetik"
(Munk, K., Ed.)
Thieme Verlag, in press
Jahn, M. & Jahn, D. (2009)
Milk fat rancidity in “Handbook of Hydrocarbon and Lipid Microbiology”
(Timmis, KN, Ed.)
Springer Verlag, Berlin, Germany in press
|
2008 |
Jahn, M. & Jahn, D. (2008)
Anpassungsfähigkeit von Mikroorganismen in “Taschenlehrbuch Biologie - Mikrobiologie” (Munk, K., Rd.)
Thieme Verlag
Dersch, P. & Jahn, D. (2008)
Mikrobielle Genetik in “Taschenlehrbuch Biologie - Mikrobiologie”
(Munk, K., Rd.)
Thieme Verlag
PUBMED: 19047738
Masoumi, A., Heinemann, I. U., Rohde, M., Koch, M., Jahn, M. & Jahn D. (2008)
Complex formation between Protoporphyrinogen IX Oxidase and Ferrochelatase during Heme Biosynthesis in Thermosynechococcus elongatus.
Microbiology. 154:3707-3714
PUBMED: 18693243
Bröcker, M., Wätzlich, D., Uliczka, F., Virus, S., Saggu, M., Lendzian, F., Scheer, H., Rüdiger, W., Moser, J. & Jahn, D. (2008)
Substrate Recognition of Nitrogenase-like Dark Operative Protochlorophyllide Oxidoreductase from Prochlorococcus marinus.
J. Biol. Chem. 283:29873-29881
PUBMED: 18832311
Benkert, B., Quäck, N., Schreiber, K., Jaensch, L., Jahn, D. & Schobert, M. (2008)
Nitrate responsive NarX-NarL represses arginine mediated induction of the Pseudomonas aeruginosa arginine fermentation arcDABC operon.
Microbiology. 154:3053-3060
PUBMED: 18440972
Klein, J., Leupold, S., Münch, R., Pommerenke, C., Johl, T., Kärst, U., Jänsch, L., Jahn, D. and Retter, I. (2008)
ProdoNet: identification and visualization of prokaryotic gene regulatory and metabolic networks.
Nucleic Acids Res. 36:W460-464
PUBMED: 18928204
Pommerenke, C., Gabriel, I., Bunk, B., Münch, R., Haddad, I., Tielen, P., Wagner-Döbler I. & Jahn D. (2008)
ROSY - a flexible and universal database and bioinformatics tool platform for Roseobacter related species.
In Silico Biol. 8:177-186
PUBMED: 18314007
Heinemann, I. U., Jahn, M. & Jahn, D. (2008)
The biochemistry of heme biosynthesis.
Arch Biochem Biophys. 474:238-251. Review
PUBMED: 18252716
Bröcker, M.J., Virus, S., Ganskow, S., Heathcote, P., Heinz, D.W., Schubert, W-D., Jahn, D. & Moser, J. (2008)
ATP-Driven Reduction by Dark-Operative Protochlorophyllide Oxidoreductase from Chlorobium tepidum Mechanistically Resembles Nitrogenase Catalysis.
J. Biol. Chem. 283:10559-10567
PUBMED: 18042043
Tan, F.-C., Cheng,Q., Saha, K., Heinemann, I. U., Jahn, M., Jahn D. & Smith, A.G. (2008)
Identification and characterization of the Arabidopsis gene encoding the tetrapyrrole biosynthesis enzyme uroporphyrinogen III synthase.
Biochem. J. 410:291-299
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2007 |
PUBMED: 17826861
Fürch, T., Wittmann, C., Wang, W., Franco-Lara, E., Jahn, D. & Deckwer, W. D. (2007)
Effect of different carbon sources on central metabolic fluxes and the recombinant production of a hydrolase from Thermobifida fusca in Bacillus megaterium.
J. Biotechnol. 132:385-394
PUBMED: 17929881
Huot, J., Balg, C., Jahn, D., Moser, J., Émond, A., Blais, S, Chênevert, R. & Lapointe, J. (2007)
Mechanism of a GatCAB amidotransferase: aspartyl-tRNA synthetase increases its affinity for Asp-tRNAAsn, and novel aa-tRNA analogs are competitive inhibitors.
Biochemistry 46:13190-13198
PUBMED: 17697121
Lüer, C., Schauer, S., Virus, S., Schubert, W.D., Heinz, D.W., Moser, J.& Jahn, D. (2007)
Glutamate Recognition and Hydride Transfer by Escherichia coli Glutamyl-tRNA Reductase.
FEBS Journal 274:4609-4614
PUBMED: 17692983
Biedendieck, R., Gamer, M., Jaensch, L., Meyer, S., Rohde, M., Deckwer, W.-D. & Jahn, D. (2007)
A sucrose-inducible promoter system for the intra- and extracellular protein production in Bacillus megaterium.
J Biotechnol. 132:426-430
PUBMED: 17608626
Homann, A., Biedendieck, R., Goetze, S., Jahn, D. & Seibel, J. (2007)
Insights into polymer versus oligosaccharide synthesis: Mutagenesis and mechanistic studies of a novel levansucrase from Bacillus megaterium.
Biochem J. 407:189-198
PUBMED: 17619232
Bäumchen, C., Roth, A. H. F. J., Biedendieck, R., Malten, M., Follmann, M., Sahm, H., Bringer-Meyer, S. & Jahn, D. (2007)
D-Mannitol production by resting state whole cell biotransformation of D-fructose by heterologous mannitol and formate dehydrogenase genes expression in Bacillus megaterium.
Biotechnol J. 2:1408-1416
PUBMED: 17657486
Vary, P. S., Biedendieck, R., Fuerch, T., Meinhardt, F., Rohde, M., Deckwer, W.-D. & Jahn, D. (2007)
Bacillus megaterium – from simple soil bacterium to industrial protein production host.
Appl Microbiol Biotechnol. 76:957-967. Review
PUBMED: Link
Klawonn, F., Choi, C., Benkert, B., Thielen, B., Münch, R., Schobert, M., Schomburg, D. & Jahn, D. (2007)
A Likelihood Ratio Test for Differential Metabolic Profiles in Multiple Intensity Measurements.
KES2007 Invited Sessions k07is-136
PUBMED: 17400734
Schreiber, K., Krieger, R., Benkert, B., Eschbach, M., Arai, H., Schobert, M. & Jahn, D. (2007)
The anaerobic regulatory network required for Pseudomonas aeruginosa nitrate respiration.
J Bacteriol. 189:4310-4314
PUBMED: Link
Choi, C., Münch, R., Bunk, B., Barthelmes, J., Ebeling, C., Schomburg, D., Schobert, M. & Jahn, D. (2007)
Combination of a data warehouse concept with web services for the establishment of the Pseudomonas systems biology database SYSTOMONAS.
Journal of Integrative Bioinformatics 4:48
PUBMED: 17224052
Jordan, E., Hust, M., Roth, A., Biedendieck, R., Schirrmann, T., Jahn, D. & Duebel, S. (2007)
Production of recombinant antibody fragments in Bacillus megaterium.
Microb Cell Fact. 6:2
PUBMED: 17134376
Heinemann, I.U., Diekmann, N., Masoumi, A., Koch, M., Messerschmidt, A., Jahn, M. & Jahn, D. (2007)
Functional definition of the tobacco protoporphyrinogen IX oxidase substrate binding site.
Biochem J. 402:575-580
PUBMED: 17245578
Biedendieck, R., Beine, R., Gamer, M., Jordan, E., Buchholz, K., Seibel, J., Dijkhuizen, L., Malten, M. & Jahn, D. (2007)
Export, purification and activities of affinity tagged Lactobacillus reuteri levansucrase produced by Bacillus megaterium.
Appl Microbiol Biotechnol. 74:1062-1073
PUBMED: 16948171
Yang, Y., Malten, M., Grote, A., Jahn, D. & Deckwer, W.D. (2007)
Codon optimized Thermobifida fusca hydrolase secreted by Bacillus megaterium.
Biotechnol Bioeng. 96:780-794
PUBMED: 16964623
Biedendieck, R., Yang, Y., Deckwer, W.-D., Malten, M. & Jahn, D. (2007)
Plasmid system for the intracellular production and purification of affinity-tagged proteins in Bacillus megaterium.
Biotechnol Bioeng. 96, 525-537
PUBMED: 17202169
Choi, C., Muench, R., Leupold, S., Klein, J., Siegel, I., Thielen, B., Benkert, B., Kucklick, M., Schobert, M., Barthelmes, J., Ebeling, C., Haddad, I., Scheer, M., Grote, A., Hiller, K., Bunk, B., Schreiber, K., Retter, I., Schomburg, D. & Jahn, D. (2007)
SYSTOMONAS - an integrated database for systems biology analysis of Pseudomonas.
Nucleic Acid Res. 35(Database Issue), D533-D537
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2006 |
Jahn, D., Moser, J., Schubert, W. & Heinz, D (2006)
Transfer RNA-dependent aminolevulinic acid formation of glutamyl-tRNA synthetase, reductase and glutamate-1-semialdehyde-2,1-aminomutase, Vol. 25, B. Grimm, R. Porra, W. Rüdiger, H. Scheer (eds.) Chlorophylls and Bacteriochlorophylls: Biochemistry, Biophysics, Functions and Applications, pp. 445-459. Springer, Dordrecht, The Netherlands
PUBMED: 17132166
Yang, Y., Biedendieck, R., Wang, W., Gamer, M., Malten, M., Jahn, D. & Deckwer, W.-D. (2006)
High yield recombinant penicillin G amidase production and export into the growth medium using Bacillus megaterium.
Microb Cell Fact. 5:36
PUBMED: 17046977
Bunk, B., Kucklick, M., Jonas, R., Munch, R., Schobert, M., Jahn, D. & Hiller, K. (2006)
MetaQuant: a tool for the automatic quantification of GC/MS based metabolome data.
Bioinformatics. 22, 2962-2965
PUBMED: 17028275
Buchenau, B., Kahnt, J., Heinemann, I.U., Jahn, D. & Thauer, R.K. (2006)
Heme biosynthesis in Methanosarcina barkeri via a pathway involving two methylation reactions.
J Bacteriol. 188, 8666-8668
PUBMED: 16885274
Haertig, E., Hartmann, A., Schatzle, M., Albertini, A.M. & Jahn, D. (2006)
The Bacillus subtilis nrdEF genes, encoding a class Ib ribonucleotide reductase, are essential for aerobic and anaerobic growth.
Appl Environ Microbiol. 72, 5260-5265
PUBMED: 16876193
Schulze, J.O., Masoumi, A., Nickel, D., Jahn, M., Jahn, D., Schubert, W.D. & Heinz D.W. (2006)
Crystal Structure of a Non-discriminating Glutamyl-tRNA Synthetase.
J Mol Biol. 361, 888-897
PUBMED: 16870933
Hiller, K., Grote, A., Maneck, M., Muench, R. & Jahn, D. (2006)
JVirGel 2.0: computational prediction of proteomes separated via two dimensional gel electrophoresis under consideration of membrane and secreted proteins.
Bioinformatics 22, 2441-2443
PUBMED: 16845060
Scheer, M., Klawonn, F., Muench, R., Grote, A., Hiller, K., Choi, C., Koch, I., Schobert, M., Haertig, E., Klages, U. & Jahn, D. (2006)
JProGO: A novel tool for the functional interpretation of prokaryotic microarray data using Gene Ontology information.
Nucleic Acids Res. 34, 510-515
PUBMED: 16796679
Reents, H., Gruner, I., Harmening, U., Böttger, L.H., Layer, G., Heathcote, P., Trautwein, A.X., Jahn,D. & Haertig, E. (2006)
Bacillus subtilis Fnr senses oxygen via a [4Fe-4S]-cluster coordinated by three cysteine residures without change in the oligomeric state.
Mol. Microbiol. 60, 1432-1445
PUBMED: 16606627
Layer, G., Pierik, A.J., Trost, M., Rigby, S.E., Leech, H.K., Grage, K., Breckau, D., Astner, I., Jaensch, L., Heathcote, P., Warren, M.J., Heinz, D.W. & Jahn,D. (2006)
The substrate radical of Escherichia coli oxygen-independent coproporphyrinogen III oxidase HemN.
J. Biol. Chem. 281. 15272-15734
PUBMED: 16567015
Sun, J., Wang, W., Hundertmark, C., Zeng, A.P., Jahn, D. & Deckwer, W.D. (2006)
A protein database constructed from low-coverage genomic sequence of Bacillus megaterium and its use for accelerated proteomic analysis.
J. Biotechnol. 124, 486-495
PUBMED: 16564539
Schulze, J.O., Schubert, W.D., Moser, J., Jahn, D. & Heinz, D.W. (2006)
Evolutionary Relationship between Initial Enzymes of Tetrapyrrole Biosynthesis.
J. Mol. Biol. 358, 1212-1220
PUBMED: 16461726
Malten, M., Biedendieck, R., Gamer, M., Drews, A.C., Stammen, S., Buchholz, K., Dijkhuizen, L. & Jahn D (2006)
A Bacillus megaterium plasmid system for the production, export, and one-step purification of affinity-tagged heterologous levansucrase from growth medium.
Appl. Environ. Microbiol. 72, 1677-1679
Deckwer, W.-D., Hempel, D.C., Zeng, A.-P. & Jahn D (2006)
Systembiotechnologische Ansätze zur Prozessentwicklung.
Chemie Ingenieur Technik 78, 193-208
Hollmann, R., Malten, M., Biedendieck, R., Yang, Y., Wang, W., Jahn, D. & Deckwer, W.-D. (2006)
Bacillus megaterium als Produktionssystem für rekombinante Proteine.
Chemie Ingenieur Technik 78, 289-294
PUBMED: 16428414
Reents, H., Muench, R., Dammeyer, T., Jahn, D. & Haertig, E. (2006)
The Fnr Regulon of Bacillus subtilis.
J. Bacteriol. 188, 1103-1112
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2005 |
PUBMED: 16109747
Muench, R., Hiller, K., Grote, A., Scheer, M., Klein, J., Schobert, M. & Jahn, D. (2005)
Virtual Footprint and PRODORIC: an integrative framework for regulon prediction in prokaryotes.
Bioinformatics 21, 4187-4189
PUBMED: 16218869
Layer, G., Kervio, E., Morlock, G., Heinz, D.W., Jahn, D., Retey, J. & Schubert, W.D. (2005)
Structural and functional comparison of HemN to other radical SAM enzymes.
Biol Chem. 386, 971-980. Review
PUBMED: 16121195
Astner, I., Schulze, J.O., van den Heuvel, J., Jahn, D., Schubert, W.D. & Heinz DW. (2005)
Crystal structure of 5-aminolevulinate synthase, the first enzyme of heme biosynthesis, and its link to XLSA in humans.
EMBO J. 24, 3166-3177
PUBMED: 15967800
Layer, G., Grage, K., Teschner, T., Schunemann, V., Breckau, D., Masoumi, A., Jahn, M., Heathcote, P., Trautwein, A.X. & Jahn, D. (2005)
Radical S-Adenosylmethionine Enzyme Coproporphyrinogen III Oxidase HemN: FUNCTIONAL FEATURES OF THE [4Fe-4S] CLUSTER AND THE TWO BOUND S-ADENOSYL-L-METHIONINES.
J. Biol. Chem. 280, 29038-29046
PUBMED: 15927046
Wang, W., Hollmann, R., Furch, T., Nimtz, M., Malten, M., Jahn, D. & Deckwer W.D. (2005)
Proteome analysis of a recombinant Bacillus megaterium strain during heterologous production of a glucosyltransferase.
Proteome Sci. 3, 4
PUBMED: 15980527
Grote, A., Hiller, K., Scheer, M., Muench, R., Noertemann, B., Hempel, D.C. & Jahn D. (2005)
JCat: a novel tool to adapt codon usage of a target gene to its potential expression host.
Nucleic Acids Res. 33, 526-531
PUBMED: 15757895
Lüer, C., Schauer, S., Moebius, K., Schulze, J., Schubert, W.-D., Heinz, D.W., Jahn, D. & Moser J.(2005)
Complex formation between glutamyl-tRNA reductase and glutamate-1-semialdehyde-2,1-aminomutase in Escherichia coli during the initial reaction of porphyrin biosynthesis.
J. Biol. Chem. 280, 18568-18572
PUBMED: 16003778
Malten, M., Nahrstedt, H., Meinhardt, F. & Jahn, D. (2005)
Coexpression of the type I signal peptidase gene sipM increases recombinant protein production and export in Bacillus megaterium MS941.
Biotechnol. Bioeng. 91, 616-621
PUBMED: 15790858
Sauerwald, A., Zhu, W., Major, T.A., Herve, R., Palioura, S., Jahn, D., Whitman, W., Yates, J.R. 3rd., Ibba, M. & Soell, D. (2005)
RNA-dependent cysteine biosynthesis in archaea.
Science 207, 1969-1972
PUBMED: 15690044
Randau, L., Münch, R., Hohn, M., Jahn, D. & Soell, D. (2005)
Nanoarchaeum equitans creates functional tRNA from separate genes encoding their 5'- and 3'-halves.
Nature 433, 537-541
PUBMED: 15644204
Frere, F., Reents, H., Schubert, W.D., Heinz, D.W., and Jahn, D.(2005)
Tracking the evolution of porphobilinogen synthase metal dependence in vitro.
J. Mol. Biol. 345, 1059-1070
PUBMED: 15593264
Malten, M., Hollmann, R., Deckwer, W.-D. & Jahn, D. (2005)
Production and secretion of recombinant Leuconostoc mesenteroides dextransucrase DsrS in Bacillus megaterium.
Biotechnol. Bioeng. 89, 206-218
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2004 |
PUBMED: 15450488
Layer, G., Heinz, D.W., Jahn, D., Schubert, W.D. (2004)
Structure and function of radical SAM enzymes.
Curr. Opin. Chem. Biol. 8, 468-476. Review
PUBMED: 15375128
Haertig, E., Geng, H., Hartmann, A., Hubacek, A., Münch, R., Ye, R. W., Jahn, D. & Nakano M. M. (2004)
Bacillus subtilis ResD Induces Expression of the Potential Regulatory Genes yclJK upon Oxygen Limitation.
J. Bacteriol. 186, 6477-6484
PUBMED: 15194701
Randau, L., Schauer, S., Ambrogelly, A., Salazar, J. C., Moser, J., Sekine, S., Yokoyama, S., Soell, D. & Jahn, D. (2004)
tRNA recognition by glutamyl-tRNA reductase.
J. Biol. Chem. 279, 34931-34937
PUBMED: 15231792
Eschbach, M., Schreiber, K., Trunk, K., Buer, J., Jahn, D. & Schobert, M. (2004)
Long-term anaerobic survival of the opportunistic pathogen Pseudomonas aeruginosa via pyruvate fermentation.
J. Bacteriol. 186, 4596-4604
PUBMED: 15215414
Hiller, K., Grote, A., Scheer, M., Muench, R. & Jahn, D. (2004)
PrediSi: prediction of signal peptides and their cleavage positions.
Nucleic Acids Res. 32, 375-379
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2003 |
Moser, J., Frere, F., Heinz, D. W., Jahn, D., and Schubert, W. (2003)
Glutamat auf Abwegen: Die tRNA-abhängige Tetrapyrrol-Biosynthese.
Biospektrum 2, 133-137
PUBMED: 14550647
Schauer, S., Lüer, C. & Moser, J. (2003)
Large Scale Production of Escherichia coli Glutamyl-tRNA Reductase.
Protein Expr. Purif. 31, 271-275
PUBMED: 14663086
Baysse, C., Matthijs, S., Schobert, M., Layer, G., Jahn, D. & Cornelis, P. (2003)
Co-ordination of iron acquisition, iron porphyrin chelation and iron-protoporphyrin export via the cytochrome c biogenesis protein CcmC in Pseudomonas fluorescens.
Microbiology 149, 3543-3552
PUBMED: 14633981
Layer, G., Moser, J., Heinz, D. W., Jahn, D. & Schubert, W. D. (2003)
Crystal structure of coproporphyrinogen III oxidase reveals cofactor geometry of Radical SAM enzymes.
EMBO J. 22, 6214-6224
PUBMED: 13680202
Frankenberg, N., Moser, J. & Jahn, D. (2003)
Bacterial heme biosynthesis and its biotechnological application.
Appl. Microbiol. Biotechnol. 63, 115-127. Review
PUBMED:12975365
Breckau, D., Mahlitz, E., Sauerwald, A., Layer, G. & Jahn, D. (2003)
Oxygen-dependent coproporphyrinogen III oxidase (HemF) from Escherichia coli is stimulated by manganese.
J. Biol. Chem. 278, 46625-46631
PUBMED:12917443
Leech, H. K., Raux, E., McLean, K. J., Munro, A. W., Robinson, N. J., Borrelly, G. P., Malten, M., Jahn, D., Rigby, S. E., Heathcote, P. & Warren, M. J. (2003)
Characterization of the cobaltochelatase CbiXL: evidence for a 4Fe-4S center housed within an MXCXXC motif.
J. Biol. Chem. 278, 41900-41907
PUBMED: 12824438
Hiller, K., Schobert, M., Hundertmark, C., Jahn, D. Muench, R. (2003)
JVirGel: Calculation of virtual two-dimensional protein gels.
Nucleic Acids Res. 31, 3862-3865
PUBMED: 12829291
Eschbach, M., Mobitz, H., Rompf, A. & Jahn, D. (2003)
Members of the genus Arthrobacter grow anaerobically using nitrate ammonification and fermentative processes: anaerobic adaptation of aerobic bacteria abundant in soil.
FEMS Microbiol. Lett. 223, 227-230.
PUBMED: 12408752
Raux, E., Leech, H. K., Beck, R., Schubert, H. L., Santander, P. J., Roessner, C. A., Scott, A. I., Martens, J. H., Jahn, D., Thermes, C., Rambach, A. & Warren, M. J. (2003)
Identification and functional analysis of enzymes required for precorrin-2 dehydrogenation and metal ion insertion in the biosynthesis of sirohaem and cobalamin in Bacillus megaterium.
Biochem J. 370, 505-516
PUBMED: 12519998
Muench, R., Hiller, K., Barg, H., Heldt, D., Linz, S., Wingender, E. & Jahn, D. (2003)
PRODORIC: Prokaryotic Database of Gene Regulation.
Nucleic Acids Res. 31, 266-269
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2002 |
PUBMED: 12520026
Finking, R., Solsbacher, J, Konz, D., Schobert, M., Schafer, A., Jahn, D. & Marahiel, M. A. (2002)
Characterization of a new type of phosphopantetheinyl transferase for fatty acid and siderophore synthesis in Pseudomonas aeruginosa.
J. Biol. Chem. 277, 50293-50302
PUBMED: 12196141
Moser, J., Schubert, W. D., Heinz, D. W. & Jahn, D. (2002)
Structure and function of glutamyl-tRNA reductase involved in 5-aminolaevulinic acid formation.
Biochem. Soc. Trans. 30, 579-584
PUBMED: 12073043
Krieger, R., Rompf, A., Schobert, M. & Jahn, D. (2002)
The Pseudomonas aeruginosa hemA promoter is regulated by Anr, Dnr, NarL and integration host factor.
Mol. Gen. Genet. 267, 409-417
Schubert, W. D., Moser, J. Schauer, S., Heinz, D. & Jahn, D. (2002)
Structure and function of glutamyl-tRNA reductase, the first enzmye of tetrapyrrole biosynthesis in plants and prokaryotes.
Photosynthesis Res., 74, 205-210
PUBMED: 12370189
Schauer, S., Chaturvedi, S., Randau, L., Moser, J., Kitabatake, M., Lorenz, S., Verkamp, E., Schubert, W. D., Nakayashiki, T., Murai, M., Wall, K., Thomann, H. U., Heinz, D. W., Inokuchi, H., Soell, D. & Jahn, D. (2002)
Escherichia coli glutamyl-tRNA reductase: Trapping of the thioester intermediate.
J. Biol. Chem., 277, 48657-48663
Löhbach, C., Bakowsky, U., Kneuer, C., Jahn, D., Graeter, T., Schäfers, H.-J. & Lehr, C.-M. (2002)
Wet chemical modification of PTFE implant surfaces with specific cell adhesion molecule.
Chem. Comm. 21, 2568-2569
PUBMED: 12114526
Layer, G., Verfurth, K., Mahlitz, E. & Jahn, D. (2002)
Oxygen-independent Coproporphyrinogen-III Oxidase HemN from Escherichia coli.
J. Biol. Chem. 277, 34136-34142.
PUBMED: 12196141
Moser, J., Schubert, W. D., Heinz, D. W. & Jahn, D. (2002)
Structure and function of glutamyl-tRNA reductase involved in 5-aminolaevulinic acid formation.
Biochem. Soc. Transac. 30, 579-584
PUBMED: 12079382
Frere, F., Schubert, W. D., Stauffer, F., Frankenberg, N., Neier, R., Jahn, D. & Heinz, D. W. (2002)
Structure of Porphobilinogen Synthase from Pseudomonas aeruginosa in Complex with 5-Fluorolevulinic Acid Suggests a Double Schiff Base Mechanism.
J. Mol. Biol. 320, 237-247
PUBMED: 11931560
Schobert, M. & Jahn, D. (2002)
Regulation of heme biosynthesis in non-phototrophic bacteria.
J. Mol. Microbiol. Biotechnol. 4, 287-294. Review
PUBMED: 11935176
Martens, J.-H., Barg, H., Warren, M. J. & Jahn, D. (2002)
Microbial Production of Vitamin B12.
Appl. Microbiol. Biotechnol. 58, 275-285. Review
|
2001 |
PUBMED: 11726494
Moser, J., Schubert, W., Beier, V., Bringemeier, I., Jahn, D. & Heinz, D. W. (2001)
V-shaped Structure of Glutamyl-tRNA-Reductase, the first Enzyme of tRNA-Dependent Tetrapyrrole Biosynthesis.
EMBO. J. 20, 6583-6590
PUBMED: 11698370
Marino, M., Cruz-Ramos, H., Hoffmann, T., Glaser, P. & Jahn, D. (2001)
Modulation of Anaerobic Energy Metabolism of Bacillus subtilis by arfM (ywiD).
J. Bacteriol. 183, 6815-6821
PUBMED: 11931560
Schobert, M. & Jahn, D. (2001)
Regulation of Heme Biosynthesis in Bacteria.
J. Mol. Microbiol. Biotechnol., 4, 287-294
|
2000 |
PUBMED: 10809684
Cruz-Ramos, H., Hoffmann, T., Marino, M., Nedjari, H., Presecan-Siedel, E., Dreesen, O., Glaser, P. & Jahn, D. (2000)
Fermentative metabolism of Bacillus subtilis: Physiology and regulation of gene expression.
J. Bacteriol. 182, 3072-3080
PUBMED: 10658656
Marino, M., Hoffmann, T., Mobitz, H., Schmid, R. & Jahn, D. (2000)
Changes in protein synthesis during the adaptation to anaerobic growth conditions in Bacillus subtilis.
Microbiology 146, 97-105
Jahn, D. (2000)
Anpassungsfähigkeit von Mikroorganismen.
In: Mikrobiologie - Lernbücher Biologie (K. Munk, Eds.). Spektrum, Akademischer Verlag
|
1999 |
PUBMED: 10498703
Homuth, G., Rompf, A. , Schumann, W. & Jahn, D. (1999)
Transcriptional control of Bacillus subtilis hemN and hemZ.
J. Bacteriol. 181, 5922-5929
PUBMED: 10521455
Moser, J., Lorenz, S. , Hubschwerlen, C., Rompf, A. & Jahn, D. (1999)
Methanopyrus kandleri glutamyl-tRNA reductase.
J. Biol. Chem. 274, 30679-30685
PUBMED: 10529244
Frankenberg, N., Jahn, D. & Jaffe, E. (1999)
Pseudomonas aeruginosa contains a novel type V porphobilinogen synthase with no required catalytic metal ions.
Biochemistry 38, 13976-13982
PUBMED: 10529243
Frankenberg, N., Heinz, D.W. & Jahn, D. (1999)
Production, purification and characterization of a Mg2+-responsive porphobilinogen synthase from Pseudomonas aeruginosa.
Biochemistry 38, 13968-13975
Frankenberg, N., Erskine, P.R., Cooper, J., Shoolingin-Jordan, P. M., Jahn, D. & Heinz, D. (1999)
High resolution crystal structure of a magnesium-dependent 5-aminolevulinic acid dehydratase.
J. Mol. Biol. 289, 591-602
Easson, E., Haltner, E., Lehr, C.-M., & Jahn, D. (1999)
Bacterial invasin factors as second generation bioadhesives.
In: Bioadhesive drug delivery systems: Fundamentals, novel approaches, and developments (Mathiowitz, E., Lehr, C-M., Chickering, D., Eds.). Begell House, Inc., New York, 405-433
Rompf, A. & Jahn, D. (1999)
Ecology of bacteria and fungi in foods: Influence of redox potential and pH.
In: Encyclopedia of Food Microbiology (Holland, T., Ed.), Academic Press Ltd., London, 556-562
|
1998 |
PUBMED: 9765565
Nakano, M.M., Hoffmann, T., Zhu, Y. & Jahn, D. (1998)
Nitrogen and oxygen regulation of Bacillus subtilis nasDEF encoding NADH-dependent nitrite reductase by TnrA and ResDE.
J. Bacteriol. 180, 5344-5350
Rajendran, N., Rompf, A., Marahiel, M.A. & Jahn, D. (1998)
Isolation and characterization of a transposon mutant of Pseudomonas fluorescens AU63 deficient in antifungal activity against Pythium ultimum.
Let. Appl. Microbiol. 27, 152-157
PUBMED: 9732527
Rompf, A., Schmid, R. & Jahn, D. (1998)
Changes in protein expression as a conseqeunce of heme depletion in Escherichia coli.
Curr. Microbiol. 37, 226-230
PUBMED: 9767567
Rompf, A., Hungerer, C., Hoffmann, T., A., Lindenmeyer, M., Romling, U., Gross, U., Doss, M.O., Arai, H., Igarashi, Y. & Jahn, D. (1998)
Regulation of Pseudomonas aeruginosa hemN and hemF by the dual action of the redox response regulators Anr and Dnr.
Mol. Microbiol. 29, 985-997
PUBMED: 9529530
Frankenberg, N., Hungerer, C., Kittel, T. & Jahn, D. (1998)
Cloning and characterisation of the Pseudomonas aeruginosa hemB encoding a magnesium-dependent aminolevulinic acid dehydratase.
Mol. Gen. Genet. 257, 485-489
PUBMED: 9396835
Lieb, C., Siddiqui, R. A., Hippler, B., Jahn, D. & Friedrich, B. (1998)
The Alcaligenes eutrophus hemN gene encoding the oxygen-independent coproporphyrinogen III oxidase is required for heme biosynthesis during anaerobic growth.
Arch. Microbiol. 169, 52-60
PUBMED: 9422613
Hoffmann, T., Frankenberg, N., Marino, M. & Jahn, D. (1998)
Ammonification in Bacillus subtilis utilizing dissimilatory nitrite reductase is dependent on resDE.
J. Bacteriol. 180, 186-189
|
1997 |
PUBMED: 9371469
Hippler, B., Homuth, G., Hoffmann, T., Schumann, W. & Jahn, D. (1997)
Characterization of Bacillus subtilis hemN.
J. Bacteriol. 179, 7181-7185
PUBMED: 9294458
Moebius, E., Jahn, M., Schmid, R., Jahn, D. & Maser, E. (1997)
Testosterone regulated expression of enzymes involved in steroid and aromatic hydrocarbon catabolism in Comamonas testosteroni.
J. Bacteriol. 179, 5951-5955
Jahn, D. (1997)
Enzymatik und Regulation der Bildung bakterieller Tetrapyrrole.
Colloquia Academica der Akademie der Wissenschaften und Literatur Mainz, 43-74
|
1996 |
Easson, J.H., Hungerer, C., Jahn, D. & Lehr, C.-M. (1996)
Bioinvasive drug carrier systems for oral delivery of peptides and proteins.
Proc. Intern. Control Rel. Bioact. Mater. 23, 1000-1001
PUBMED: 8831980
Hungerer, C., Weiss, D., Thauer, R.K. & Jahn, D. (1996)
Cloning, characterization and expression of the Methanobacterium thermoautotrophicum hemA gene encoding glutamyl-tRNA reductase.
Bioorg. Med. Chem. 7, 1089-1095
Jahn, D., Hungerer, C. & Troup, B. (1996)
Ungewöhnliche Schritte und umweltregulierte Gene der bakteriellen Hämbiosynthese.
Naturwissenschaften 83, 389-400. Review
Jahn, D., Hungerer, C. & Troup, B. (1996)
Die bakterielle Hämbiosynthese: Alternative Wege und umweltgesteuerte Genexpression.
Biospektrum 2, 22-27
|
1995 |
PUBMED: 7557333
Hoffmann, T., Troup, B., Szabo, A., Hungerer, C. & Jahn, D. (1995)
The anaerobic life of Bacillus subtilis. Cloning and characterization of the genes encoding the respiratory nitrate reductase system.
FEMS Microbiol. Let. 131, 219-225
PUBMED: 7565600
Hungerer, C., Troup, B., Romling, U. & Jahn, D. (1995)
Cloning, mapping and characterization of the Pseudomonas aeruginosa hemL gene.
Mol. Gen. Genet. 248, 375-380
PUBMED: 7768836
Troup, B., Hungerer, C. & Jahn, D. (1995)
Cloning and characterization of the Escherichia coli hemN gene encoding the oxygen- independent coproporphyrinogen III oxidase.
J. Bacteriol. 177, 3326-3331
PUBMED: 7883699
Hungerer, C., Troup, B., Romling, U. & Jahn, D. (1995)
Regulation of the hemA gene during 5-aminolevulinic acid formation in Pseudomonas aeruginosa.
J. Bacteriol. 177, 1435-1443
|
1994 |
PUBMED: 8300522
Troup, B., Jahn, M., Hungerer, C. & Jahn, D. (1994)
Isolation of the hemF operon containing the gene for the Escherichia coli aerobic coproporphyrinogen III oxidase by in vivo complementation of a yeast HEM13 mutant.
J. Bacteriol. 176, 673-680
PUBMED: 8138133
Rajendran, N., Jahn, D., Jayaraman, K. & Marahiel, M.A. (1994)
Transposon Tn5 mutagenesis of Pseudomonas fluorescens to isolate mutants deficient in antibacterial activity.
FEMS Microbiol. Let. 115, 191-196
|
1993 1992 |
Jahn, D., Verkamp, E. & Soell, D (1992)
Glutamyl-transfer RNA: a precursor of heme and chlorophyll biosynthesis.
Trends Biol. Sci. 17, 215-219. Review
aktualisiert 23.08.2010
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Verantwortlich:
Simon Stammen
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